4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate

Base Information

Chemical Name:4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate
CAS No.:133283-84-8
Molecular Formula:C₁₆H₂₀O₂
Molecular Weight:244.334
Hs Code.:

Synonyms:

Suppliers and Price of 4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate

There total 5 articles about 4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 133283-83-7,133283-89-3
1-bromo-4-methyl-4-(4-methylphenyl)-hex-5-yn-2-ol

: 133283-85-9
4-methyl-4-(4-methylphenyl)-hex-5-yn-1-ol-acetate

: 133283-84-8,133283-87-1
4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate

Guidance literature:: With tributyltin chloride; sodium cyanoborohydride; 2,2'-azobis(isobutyronitrile); In butan-1-ol; for 3h; Heating;
DOI:10.1016/S0040-4020(01)90504-6

Reference yield:

: 79443-97-3
methyl 2-(4-methylphenyl)propanoate

: 133283-84-8,133283-87-1
4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate

Guidance literature:: Multi-step reaction with 6 steps

1: 1) LDA / 1) THF, -70 deg C, 1h, 2) -70 deg C to RT, 2h

2: 90 percent / LiAlH₄ / diethyl ether / 16 h / Ambient temperature

3: PCC / CH₂Cl₂ / 4 h / Ambient temperature

4: 1) Ph₃P, 2) n-BuLi / 1) CH₂Cl₂, 0 deg C, 1h, 2) THF,m a) -70 deg C, 1h, b) RT, 0.5h

5: 91 percent / NBS / CH₂Cl₂; acetic acid / 16 h / Ambient temperature

6: 41 percent / n-Bu₃SnCl, NaCNBH₃ / AIBN / butan-1-ol / 3 h / Heating

With N-Bromosuccinimide; lithium aluminium tetrahydride; n-butyllithium; tributyltin chloride; sodium cyanoborohydride; triphenylphosphine; pyridinium chlorochromate; lithium diisopropyl amide; 2,2'-azobis(isobutyronitrile); In diethyl ether; dichloromethane; acetic acid; butan-1-ol;
DOI:10.1016/S0040-4020(01)90504-6

Reference yield:

: 125403-42-1
2-methyl-2-(4-methylphenyl)-pent-4-en-1-ol

: 133283-84-8,133283-87-1
4-methyl-4-(4-methylphenyl)-3-methylenecyclopentanol acetate

Guidance literature:: Multi-step reaction with 4 steps

1: PCC / CH₂Cl₂ / 4 h / Ambient temperature

2: 1) Ph₃P, 2) n-BuLi / 1) CH₂Cl₂, 0 deg C, 1h, 2) THF,m a) -70 deg C, 1h, b) RT, 0.5h

3: 91 percent / NBS / CH₂Cl₂; acetic acid / 16 h / Ambient temperature

4: 41 percent / n-Bu₃SnCl, NaCNBH₃ / AIBN / butan-1-ol / 3 h / Heating

With N-Bromosuccinimide; n-butyllithium; tributyltin chloride; sodium cyanoborohydride; triphenylphosphine; pyridinium chlorochromate; 2,2'-azobis(isobutyronitrile); In dichloromethane; acetic acid; butan-1-ol;
DOI:10.1016/S0040-4020(01)90504-6