Technology Process of (S)-1-(benzyloxycarbonyl)-2-methylpropyl 4'-octoxybiphenyl-4-ylethanoate
There total 8 articles about (S)-1-(benzyloxycarbonyl)-2-methylpropyl 4'-octoxybiphenyl-4-ylethanoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide;
In
dichloromethane;
for 6h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) NaNO2, 0.5 M H2SO4, 2.) NaOH / 1.) water, -2-0 deg C, 3 h, overnight, room temp., 2.) water, pH=4.5-5.0
2: 96 percent / dimethylformamide / 24 h / Ambient temperature
3: 83 percent / DCC, 4-(N-pyrrolidino)pyridine / CH2Cl2 / 6 h / Ambient temperature
With
sodium hydroxide; sulfuric acid; 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide; sodium nitrite;
In
dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 41 percent / 60percent HBr / acetic acid / 6 h / Heating
2: 93 percent / anhydrous K2CO3 / butan-2-one / 48 h / Heating
3: 93 percent / S / 5 h / Heating
4: 56 percent / NaOH / ethanol / 10 h / Heating
5: 83 percent / DCC, 4-(N-pyrrolidino)pyridine / CH2Cl2 / 6 h / Ambient temperature
With
sodium hydroxide; hydrogen bromide; potassium carbonate; 4-pyrrolidin-1-ylpyridine; sulfur; dicyclohexyl-carbodiimide;
In
ethanol; dichloromethane; acetic acid; butanone;
