BocDAsp(OBzl)Lys(Z)ProOBzl

Base Information

• Chemical Name: BocDAsp(OBzl)Lys(Z)ProOBzl
• CAS No.: 127103-26-8
• Molecular Formula: C₄₂H₅₂N₄O₁₀
• Molecular Weight: 772.896
• Mol file: 127103-26-8.mol

Synonyms:

Chemical Property of BocDAsp(OBzl)Lys(Z)ProOBzl

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of BocDAsp(OBzl)Lys(Z)ProOBzl

There total 1 articles about BocDAsp(OBzl)Lys(Z)ProOBzl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-benzyl Boc-D-aspartate (51186-58-4,98482-77-0) + benzyl N6-((benzyloxy)carbonyl)-L-lysyl-L-prolinate trifluoroacetate (68280-76-2) → BocDAsp(OBzl)Lys(Z)ProOBzl (127103-26-8)

Guidance literature:

With 4-methyl-morpholine; isobutyl chloroformate; Yield given. Multistep reaction; 1.) THF, -15 deg C, 5 min, 2.) DMF, 1 h;

DOI:10.1021/jm00170a012

Reference yield:

BocDAsp(OBzl)Lys(Z)ProOBzl (127103-26-8) + trifluoroacetic acid (76-05-1) → (S)-1-[(S)-2-((R)-2-Amino-3-benzyloxycarbonyl-propionylamino)-6-benzyloxycarbonylamino-hexanoyl]-pyrrolidine-2-carboxylic acid benzyl ester; compound with trifluoro-acetic acid

Guidance literature:

In dichloromethane; Ambient temperature;

DOI:10.1021/jm00170a012

upstream raw materials:

4-benzyl Boc-D-aspartate

benzyl N⁶-((benzyloxy)carbonyl)-L-lysyl-L-prolinate trifluoroacetate