C₁₂H₁₆BrNO

Base Information

• Chemical Name: C₁₂H₁₆BrNO
• CAS No.: 945670-26-8
• Molecular Formula: C₁₂H₁₆BrNO
• Molecular Weight: 270.169
• Mol file: 945670-26-8.mol

Synonyms:

Chemical Property of C₁₂H₁₆BrNO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₆BrNO

There total 1 articles about C₁₂H₁₆BrNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-methyl-3-phenylpropylamine (4187-57-9,22148-77-2,1199266-89-1) + bromoacetic acid (79-08-3) → C12H16BrNO (945670-26-8)

Guidance literature:

With dmap; 1-[3-(dimethylamino)-propyl]-3-ethylcarbodiimide methiodide; In dichloromethane; at 20 ℃; for 8h;

DOI:10.1039/b702572f

Reference yield:

C12H16BrNO (945670-26-8) → C17H20N2O2

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate; NaY zeolite / acetonitrile / 0.5 h / Heating

1.2: acetonitrile / 12 h / Heating

2.1: RbY zeolite / CH₂Cl₂; hexane / 2 h / Irradiation

With NaY zeolite; RbY zeolite; potassium carbonate; In hexane; dichloromethane; acetonitrile;

DOI:10.1039/b702572f

Reference yield:

2-hydroxypyridin (142-08-5) + C12H16BrNO (945670-26-8) → C17H20N2O2 (945670-54-2)

Guidance literature:

2-hydroxypyridin; With NaY zeolite; potassium carbonate; In acetonitrile; for 0.5h; Heating;

C₁₂H₁₆BrNO; In acetonitrile; for 12h; Further stages.; Heating;

DOI:10.1039/b702572f

upstream raw materials:

(S)-1-methyl-3-phenylpropylamine

bromoacetic acid

Downstream raw materials:

C₁₇H₂₀N₂O₂