Technology Process of ethyl 5-chloro-2,4-dihydroxy-3-methyl-6-s-butylbenzoate
There total 1 articles about ethyl 5-chloro-2,4-dihydroxy-3-methyl-6-s-butylbenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: K2CO3 / acetone / Heating
2: 4.8 g / BCl3 / CH2Cl2 / 0 deg C, 0.5 h -> room temperature, 1 h
3: K2CO3 / dimethylformamide / 24 h
4: 4.8 g / KOH (aq) / dimethylsulfoxide / 27.5 h / Heating
5: 6.1 g / trifluoroacetic anhydride / CH2Cl2 / 2.5 h
6: 3.3 g / H2, HCl (conc) / Pd-C / ethyl acetate
With
hydrogenchloride; potassium hydroxide; hydrogen; boron trichloride; potassium carbonate; trifluoroacetic anhydride;
palladium on activated charcoal;
In
dichloromethane; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetone;
DOI:10.1039/P19810000874
- Guidance literature:
-
Multi-step reaction with 4 steps
1: K2CO3 / acetone / Heating
2: 4.8 g / BCl3 / CH2Cl2 / 0 deg C, 0.5 h -> room temperature, 1 h
3: K2CO3 / dimethylformamide / 24 h
4: 4.8 g / KOH (aq) / dimethylsulfoxide / 27.5 h / Heating
With
potassium hydroxide; boron trichloride; potassium carbonate;
In
dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
DOI:10.1039/P19810000874
