Technology Process of C23H19F3N4O2
There total 6 articles about C23H19F3N4O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
tetrahydrofuran;
at 20 ℃;
DOI:10.1021/ml200261d
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrogenchloride / water; acetic acid / 110 °C
2: sulfuric acid / 80 °C
3: palladium diacetate; caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene / 1,4-dioxane / 110 °C
4: palladium 10% on activated carbon; hydrogen / acetic acid / 20 °C
5: triethylamine / tetrahydrofuran / 20 °C
With
hydrogenchloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; palladium diacetate; caesium carbonate; triethylamine; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
tetrahydrofuran; 1,4-dioxane; water; acetic acid;
DOI:10.1021/ml200261d
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 110 °C
2: palladium 10% on activated carbon; hydrogen / acetic acid / 20 °C
3: triethylamine / tetrahydrofuran / 20 °C
With
palladium 10% on activated carbon; hydrogen; palladium diacetate; caesium carbonate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
tetrahydrofuran; 1,4-dioxane; acetic acid;
DOI:10.1021/ml200261d