5-BROMO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULENE

Base Information

• Chemical Name: 5-BROMO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULENE
• CAS No.: 128364-39-6
• Molecular Formula: C₁₁H₁₃Br
• Molecular Weight: 225.128
• Mol file: 128364-39-6.mol

Synonyms:

Chemical Property of 5-BROMO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULENE

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

5-bromo-6,7,8,9-tetrahydro-5H-benzo[7]annulene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-BROMO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULENE

There total 2 articles about 5-BROMO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-benzosuberol (35550-94-8,65915-63-1,79416-49-2,138381-73-4) → 5-bromo-6,7,8,9-tetrahydro-5H-benzocycloheptene (128364-39-6)

Guidance literature:

With phosphorus tribromide; for 2h;

Reference yield:

1-Benzosuberone (826-73-3) → 5-bromo-6,7,8,9-tetrahydro-5H-benzocycloheptene (128364-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: 89 percent / PBr₃ / 2 h

With lithium aluminium tetrahydride; phosphorus tribromide; In diethyl ether;

upstream raw materials:

1-benzosuberol

1-Benzosuberone

Refernces

• 1、 Binder, Joerg T.,Cordier, Christopher J.,Fu, Gregory C.. "Catalytic enantioselective cross-couplings of secondary alkyl electrophiles with secondary alkylmetal nucleophiles: Negishi reactions of racemic benzylic bromides with achiral alkylzinc reagents". supporting information. p. 17003 - 17006. Retrieved 2013/01/15.