4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide

Base Information

• Chemical Name: 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide
• CAS No.: 1174284-15-1
• Molecular Formula: C₂₈H₃₆N₄O₅S
• Molecular Weight: 540.684

Synonyms:

Chemical Property of 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide

There total 1 articles about 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R,S)-3-(naphthalene-2-sulfonamido)-3-phenylpropanoic acid (193633-65-7) + [2-[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]methylamino]ethoxy]acetic acid (766558-33-2) + tert-butyl 6-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (1174068-65-5) + tert-butyl 6-(pyridin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (1174068-62-2) + tert-butyl 2-(pyridin-4-yl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate (1174068-68-8) + tert-butyl 6-(pyridin-4-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (1174068-63-3) + tert-butyl 6-(pyridin-3-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (1174068-66-6) + tert-butyl 2-(pyridin-4-ylmethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate (1174068-69-9) + tert-butyl 6-(2-(pyridin-3-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (1174068-67-7) + tert-butyl 6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (1174068-64-4) + tert-butyl 2-(2-(pyridin-4-yl)ethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate (1174068-70-2) → 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(pyridin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-20-8) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-07-1) + N-(3-Oxo-1-phenyl-3-(6-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)propyl)naphthalene-2-sulfonamide (1174284-08-2) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(2-(pyridin-4-yl)-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-18-4) + N-(3-Oxo-1-phenyl-3-(6-(pyridin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)propyl)naphthalene-2-sulfonamide (1174284-09-3) + N-(3-Oxo-1-phenyl-3-(6-(pyridin-4-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)propyl)naphthalene-2-sulfonamide (1174284-11-7) + N-(3-Oxo-1-phenyl-3-(6-(pyridin-3-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)propyl)naphthalene-2-sulfonamide (1174284-19-5) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(pyridin-4-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-06-0) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(pyridin-3-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-17-3) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(2-(pyridin-4-ylmethyl)-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-23-1) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(2-(pyridin-3-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-13-9) + N-(3-Oxo-1-phenyl-3-(6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)propyl)naphthalene-2-sulfonamide (1174284-16-2) + N-(3-Oxo-1-phenyl-3-(6-(2-(pyridin-3-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)propyl)naphthalene-2-sulfonamide (1174284-14-0) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(2-(2-(pyridin-4-yl)ethyl)-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-22-0) + 4-Methoxy-N,2,6-trimethyl-N-(2-(2-oxo-2-(6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide (1174284-15-1)

Guidance literature:

tert-butyl 6-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate; tert-butyl 6-(pyridin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate; tert-butyl 2-(pyridin-4-yl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate; tert-butyl 6-(pyridin-4-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate; tert-butyl 6-(pyridin-3-ylmethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate; tert-butyl 2-(pyridin-4-ylmethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate; tert-butyl 6-(2-(pyridin-3-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate; tert-butyl 6-(2-(pyridin-4-yl)ethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate; tert-butyl 2-(2-(pyridin-4-yl)ethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate; With trifluoroacetic acid; In dichloromethane; at 0 - 25 ℃; for 4h; Combinatorial reaction / High throughput screening (HTS);

(R,S)-3-(naphthalene-2-sulfonamido)-3-phenylpropanoic acid; [2-[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]methylamino]ethoxy]acetic acid; With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 25 ℃; for 16h; Combinatorial reaction / High throughput screening (HTS);

upstream raw materials:

(R,S)-3-(naphthalene-2-sulfonamido)-3-phenylpropanoic acid

[2-[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]methylamino]ethoxy]acetic acid

tert-butyl 6-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate

tert-butyl 6-(pyridin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate

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