N-[5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]urea

Base Information

Chemical Name:N-[5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]urea
CAS No.:87657-92-9
Molecular Formula:C₁₀H₉ClN₄O₃
Molecular Weight:268.659
Hs Code.:
DSSTox Substance ID:DTXSID501201258

Synonyms:DTXSID501201258;N-[5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]urea;87657-92-9

Suppliers and Price of N-[5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]urea

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:268.0363179
Heavy Atom Count:18
Complexity:286

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1OCC2=NN=C(O2)NC(=O)N)Cl

Technology Process of N-[5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]urea

There total 2 articles about N-[5-[(4-Chlorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 122-88-3
4-Chlorophenoxyacetic acid

: 87657-92-9
[5-(4-Chloro-phenoxymethyl)-[1,3,4]oxadiazol-2-yl]-urea

Guidance literature:: Multi-step reaction with 2 steps

1: conc. H₂SO₄ / 4 h / 60 - 80 °C

2: glacial acetic acid / H₂O / 1.5 h / Ambient temperature

With sulfuric acid; acetic acid; In water;
DOI:10.1002/ardp.19833160913

Reference yield:

: 590-28-3
potassium cyanate

: 21520-97-8
5-(4-chloro-phenoxymethyl)-[1,3,4]oxadiazol-2-ylamine

: 87657-92-9
[5-(4-Chloro-phenoxymethyl)-[1,3,4]oxadiazol-2-yl]-urea

Guidance literature:: With acetic acid; In water; for 1.5h; Yield given; Ambient temperature;
DOI:10.1002/ardp.19833160913

Reference yield:

: 87657-92-9
[5-(4-Chloro-phenoxymethyl)-[1,3,4]oxadiazol-2-yl]-urea

: 87658-03-5
1-[5-(4-Chloro-phenoxymethyl)-[1,3,4]oxadiazol-2-yl]-5-[1-phenyl-meth-(Z)-ylidene]-imidazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine

2: acetic anhydride, CH₃COONa / acetic acid / 8 h / 140 - 150 °C

With sodium acetate; acetic anhydride; In pyridine; acetic acid;
DOI:10.1002/ardp.19833160913