Technology Process of USDA 19
There total 5 articles about USDA 19 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: i-Pr2NEt, Ag2CO3, P(o-Tol)3 / Pd(OAc)2 / dimethylformamide / 100 °C
2: HCO2NH4 / Pd/C / methanol / 4 h / Heating
3: LiAlH4 / diethyl ether / 2 h / Heating
4: aq. HBr
With
lithium aluminium tetrahydride; hydrogen bromide; ammonium formate; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; silver carbonate;
palladium diacetate; palladium on activated charcoal;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(96)00618-X
- Guidance literature:
-
Multi-step reaction with 3 steps
1: HCO2NH4 / Pd/C / methanol / 4 h / Heating
2: LiAlH4 / diethyl ether / 2 h / Heating
3: aq. HBr
With
lithium aluminium tetrahydride; hydrogen bromide; ammonium formate;
palladium on activated charcoal;
In
methanol; diethyl ether;
DOI:10.1016/S0960-894X(96)00618-X
- Guidance literature:
-
Multi-step reaction with 4 steps
1: i-Pr2NEt, Ag2CO3, P(o-Tol)3 / Pd(OAc)2 / dimethylformamide / 100 °C
2: HCO2NH4 / Pd/C / methanol / 4 h / Heating
3: LiAlH4 / diethyl ether / 2 h / Heating
4: aq. HBr
With
lithium aluminium tetrahydride; hydrogen bromide; ammonium formate; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; silver carbonate;
palladium diacetate; palladium on activated charcoal;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(96)00618-X
