4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)-

Base Information

• Chemical Name: 4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)-
• CAS No.: 1005509-36-3
• Molecular Formula: C₁₀H₈ClN₃O₂
• Molecular Weight: 237.645
• Mol file: 1005509-36-3.mol

Synonyms:

Chemical Property of 4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)-

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

5-Amino-3-(3-chlorophenyl)isoxazole-4-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)-

There total 1 articles about 4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-N-hydroxybenzimidoyl chloride (29203-59-6) + cyanoacetic acid amide (107-91-5) → C10H8ClN3O2 (1005509-36-3)

Guidance literature:

cyanoacetic acid amide; With sodium ethanolate; In ethanol; Heating;

3-chloro-N-hydroxybenzimidoyl chloride; In ethanol; Cooling; Reflux;

DOI:10.1055/s-0029-1219781

Reference yield:

C10H8ClN3O2 (1005509-36-3) + orthoformic acid triethyl ester (122-51-0) → C11H6ClN3O2 (1233656-02-4)

Guidance literature:

With acetic anhydride; Reflux;

DOI:10.1055/s-0029-1219781

upstream raw materials:

3-chloro-N-hydroxybenzimidoyl chloride

cyanoacetic acid amide

Downstream raw materials:

C₁₁H₆ClN₃O₂

Refernces