O-ethyl-O-(4-trifluoromethylphenyl)-N-cyclohexyl phosphoramidate

Base Information

• Chemical Name: O-ethyl-O-(4-trifluoromethylphenyl)-N-cyclohexyl phosphoramidate
• CAS No.: 1338561-75-3
• Molecular Formula: C₁₅H₂₁F₃NO₃P
• Molecular Weight: 351.306
• Mol file: 1338561-75-3.mol

Synonyms:

Chemical Property of O-ethyl-O-(4-trifluoromethylphenyl)-N-cyclohexyl phosphoramidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of O-ethyl-O-(4-trifluoromethylphenyl)-N-cyclohexyl phosphoramidate

There total 1 articles about O-ethyl-O-(4-trifluoromethylphenyl)-N-cyclohexyl phosphoramidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxybenzotrifluoride (402-45-9) → O-ethyl-O-(4-trifluoromethylphenyl)-N-cyclohexyl phosphoramidate (1338561-75-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 0 °C / Inert atmosphere

2: triethylamine / tetrahydrofuran / 0 °C / Inert atmosphere

With triethylamine; In tetrahydrofuran;

DOI:10.1016/j.bmcl.2011.07.088

upstream raw materials:

4-hydroxybenzotrifluoride