3-Chloro-1-Methyl-pyrrolidine

Base Information

• Chemical Name: 3-Chloro-1-Methyl-pyrrolidine
• CAS No.: 10603-46-0
• Molecular Formula: C₅H₁₀ClN
• Molecular Weight: 119.594
• Hs Code.: 2933990090
• Mol file: 10603-46-0.mol

Synonyms:3-Chlor-1-methyl-pyrrolidin;3-Chloro-1-methyl-pyrrolidine;1-Methyl-3-chlor-pyrrolidin;1-methyl-3-chloropyrrolidine;

Chemical Property of 3-Chloro-1-Methyl-pyrrolidine

Chemical Property:

• PSA: 3.24000
• LogP: 0.86720

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-chloro-1-methylpyrrolidine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Chloro-1-Methyl-pyrrolidine

There total 2 articles about 3-Chloro-1-Methyl-pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methyl-3-pyrrolidinol (13220-33-2,99445-21-3) → 3-chloro-1-methyl pyrrolidine (10603-46-0,1353997-39-3)

Guidance literature:

In chloroform;

Reference yield:

→ 3-chloro-1-methyl pyrrolidine (10603-46-0,1353997-39-3)

Guidance literature:

nach Franko, Lunsford, J. med. Chem. 2 <1960> 523;

DOI:10.1021/jm00333a012

Reference yield:

3-chloro-1-methyl pyrrolidine (10603-46-0,1353997-39-3) + benzylamine (100-46-9) → benzyl-(1-methyl-pyrrolidin-3-yl)-amine (64021-80-3)

Guidance literature:

In diethyl ether; ethanol;

upstream raw materials:

1-methyl-3-pyrrolidinol

Downstream raw materials:

benzyl-(1-methyl-pyrrolidin-3-yl)-amine

Refernces

• 1、 -. "N-substituted 3-aminopyrrolidines". . . Retrieved 2008/06/13.