cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine

Base Information

• Chemical Name: cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine
• CAS No.: 158478-42-3
• Molecular Formula: C₂₀H₂₉N
• Molecular Weight: 283.457
• Mol file: 158478-42-3.mol

Synonyms:

Chemical Property of cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine

There total 2 articles about cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 1.0%

cis-N-(benzenesulfenyl)-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine (158478-41-2) → cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine (158478-42-3) + (4aR,8aR,9S,9aS)-9-(4-Isopropyl-phenyl)-decahydro-pyrrolo[1,2-a]indole

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 6h; Heating;

DOI:10.1016/S0040-4020(01)80838-3

Reference yield:

rac-3-bromocyclohexene (1521-51-3,113667-32-6) + cis-5-(4-isopropylphenyl)pent-4-enylamine (154777-53-4) → cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine (158478-42-3)

Guidance literature:

for 18h; Heating;

DOI:10.1016/S0040-4020(01)80838-3

Reference yield:

cis-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine (158478-42-3) → (4aR,8aR,9S,9aS)-9-(4-Isopropyl-phenyl)-decahydro-pyrrolo[1,2-a]indole

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / diethyl ether / 2.5 h / Ambient temperature

2: 14 percent / Bu₃SnH, AIBN / benzene / 6 h / Heating

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; triethylamine; In diethyl ether; benzene;

DOI:10.1016/S0040-4020(01)80838-3

upstream raw materials:

rac-3-bromocyclohexene

cis-5-(4-isopropylphenyl)pent-4-enylamine

cis-N-(benzenesulfenyl)-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine

Downstream raw materials:

cis-N-(benzenesulfenyl)-N-(cyclohex-2-en-1-yl)-5-(4-isopropylphenyl)pent-4-enylamine