Dipipanone

Base Information

• Chemical Name: Dipipanone
• CAS No.: 467-83-4
• Deprecated CAS: 27453-70-9,856-87-1
• Molecular Formula: C24H31 N O
• Molecular Weight: 349.516
• Hs Code.: 2933330031
• European Community (EC) Number: 207-399-2
• UNII: X188638Y2V
• DSSTox Substance ID: DTXSID50894759
• Nikkaji Number: J5.913G
• Wikipedia: Dipipanone
• Wikidata: Q4162039
• NCI Thesaurus Code: C65426
• Metabolomics Workbench ID: 146146
• ChEMBL ID: CHEMBL2111157
• Mol file: 467-83-4.mol

Synonyms:4,4-diphenyl-6-piperidino-3-heptanone;dipipanone;dipipanone hydrochloride;dipipanone hydrochloride, (+-)-isomer

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Dipipanone

Chemical Property:

• Vapor Pressure: 7.65E-10mmHg at 25°C
• Boiling Point: 492.5°Cat760mmHg
• PKA: pKa 8.5 (Uncertain)
• Flash Point: 178.8°C
• PSA: 20.31000
• Density: 1.035g/cm³
• LogP: 5.15420
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 349.240564612
• Heavy Atom Count: 26
• Complexity: 410

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)C(CC(C)N1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3
• Uses: Controlled sustance (opiate). Analgesic (narcotic).

Technology Process of Dipipanone

There total 11 articles about Dipipanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4-diphenyl-6-piperidino-heptan-3-one-imine (24153-57-9) → dipipanone (467-83-4,856-87-1)

Guidance literature:

With hydrogenchloride;

DOI:10.1039/jr9500002158

Reference yield:

Diphenylacetonitrile (86-29-3) → dipipanone (467-83-4,856-87-1)

Guidance literature:

Multi-step reaction with 3 steps

1: phenyl lithium; diethyl ether; diethylamine

2: xylene

3: aqueous hydrochloric acid

With hydrogenchloride; diethyl ether; phenyllithium; diethylamine; xylene;

DOI:10.1039/jr9500002158

Reference yield:

1-(2-chloro-propyl)-piperidine (698-92-0) → dipipanone (467-83-4,856-87-1)

Guidance literature:

Multi-step reaction with 3 steps

1: phenyl lithium; diethyl ether; diethylamine

2: xylene

3: aqueous hydrochloric acid

With hydrogenchloride; diethyl ether; phenyllithium; diethylamine; xylene;

DOI:10.1039/jr9500002158

upstream raw materials:

4,4-diphenyl-6-piperidino-heptan-3-one-imine

piperidine

1-(2-chloro-propyl)-piperidine

1-(2-chloro-1-methyl-ethyl)-piperidine