1-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

Base Information

Chemical Name:1-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
CAS No.:179343-18-1
Molecular Formula:C₂₀H₂₄N₆O
Molecular Weight:364.45
Hs Code.:
DSSTox Substance ID:DTXSID501123719
Nikkaji Number:J864.914F
ChEMBL ID:CHEMBL57323

Synonyms:CHEMBL57323;1-[2-amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea;6-arylpyrido[2,3-d]pyrimidine deriv. 15;BDBM3433;SCHEMBL8120559;DTXSID501123719;N-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea;179343-18-1

Suppliers and Price of 1-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:364.20115941
Heavy Atom Count:27
Complexity:511

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)C)C2=C(N=C3C(=C2)C=NC(=N3)N)NC(=O)NC(C)(C)C

Technology Process of 1-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

There total 4 articles about 1-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20781-06-0
2,4-diamino-5-pyrimidinecarboxaldehyde

: 179343-18-1
1-[2-amino-6-(2,6-dimethylphenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / 2-ethoxy-ethanol / Heating

2: 1) NaH / 1) DMF, room temperature, 1 h

With sodium hydride; In 2-ethoxy-ethanol;
DOI:10.1016/S0960-894X(97)00445-9

Reference yield:

: 54708-14-4
2,6-dimethylphenylacetonitrile

: 179343-18-1
1-[2-amino-6-(2,6-dimethylphenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / 2-ethoxy-ethanol / Heating

2: 1) NaH / 1) DMF, room temperature, 1 h

With sodium hydride; In 2-ethoxy-ethanol;
DOI:10.1016/S0960-894X(97)00445-9