C₂₀H₂₅NOS

Base Information

• Chemical Name: C₂₀H₂₅NOS
• CAS No.: 1428366-50-0
• Molecular Formula: C₂₀H₂₅NOS
• Molecular Weight: 327.491
• Mol file: 1428366-50-0.mol

Synonyms:

Chemical Property of C₂₀H₂₅NOS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₅NOS

There total 6 articles about C₂₀H₂₅NOS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C17H19NOS + allylmagnesium bromide (1730-25-2) → C20H25NOS (1428366-50-0)

Guidance literature:

In toluene; at 20 ℃; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/jo400354r

Reference yield:

C15H27NOSSi (1428366-12-4) → C20H25NOS (1428366-50-0)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2: titanium(IV) tetraethanolate / dichloromethane / Inert atmosphere; Reflux

3: toluene / 20 °C / Inert atmosphere

With titanium(IV) tetraethanolate; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1021/jo400354r

Reference yield:

(Rs)-2-phenylpropyl-2-sulfinamide (1428365-94-9) → C20H25NOS (1428366-50-0)

Guidance literature:

Multi-step reaction with 2 steps

1: titanium(IV) tetraethanolate / dichloromethane / Inert atmosphere; Reflux

2: toluene / 20 °C / Inert atmosphere

With titanium(IV) tetraethanolate; In dichloromethane; toluene;

DOI:10.1021/jo400354r

upstream raw materials:

C₁₅H₂₇NOSSi

(R_s)-2-phenylpropyl-2-sulfinamide

α,α-dimethylbenzylmercaptan

bis(1-methyl-1-phenylethyl)disulfide

Refernces