Technology Process of C20H34OSi2
There total 1 articles about C20H34OSi2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
trimethylsilylacetylene;
With
isopropylmagnesium chloride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 1h;
With
copper(I) bromide;
In
tetrahydrofuran;
at 20 ℃;
for 0.5h;
C15H25BrOSi;
In
tetrahydrofuran;
for 5h;
Reflux;
DOI:10.1039/c3ob41214h
- Guidance literature:
-
With
tetrabutyl ammonium fluoride; acetic acid;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 18h;
DOI:10.1039/c3ob41214h
- Guidance literature:
-
Multi-step reaction with 4 steps
1: acetic acid; tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 0 - 20 °C
2: copper(I) oxide / water; ethyl acetate / 20 °C
3: thionyl chloride / dichloromethane / 20 °C
4: potassium hydroxide / acetonitrile / 48.33 h / 20 °C / Inert atmosphere; Reflux
With
copper(I) oxide; thionyl chloride; tetrabutyl ammonium fluoride; acetic acid; potassium hydroxide;
In
tetrahydrofuran; dichloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1039/c3ob41214h