4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Base Information

Chemical Name:4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine
CAS No.:1092789-28-0
Molecular Formula:C₆H₄ClIN₄
Molecular Weight:294.482
Hs Code.:

Synonyms:

Suppliers and Price of 4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 95%
1g
$ 740.00

Crysdot
4-Chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 97%
1g
$ 447.00

Chemenu
4-Chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 97%
1g
$ 422.00

Total 1 raw suppliers

Chemical Property of 4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Chemical Property:

Purity/Quality:: 4-Chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

There total 2 articles about 4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1415638-01-5
3-iodo-1-methyl-I H-pyrazolo[3,4-d]pyrimidin-4-ol

: 1092789-28-0
4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Guidance literature:: With trichlorophosphate; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; at 80 ℃; for 2h;

Reference yield:

: 5334-56-5
4-hydroxy-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

: 1092789-28-0
4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrafluoroboric acid; N-iodo-succinimide / acetonitrile; water / 5 h / Reflux

2: trichlorophosphate / N,N-dimethyl-formamide; 1,2-dichloro-ethane / 2 h / 80 °C

With N-iodo-succinimide; tetrafluoroboric acid; trichlorophosphate; In water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 1092789-28-0
4-chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

: 1415637-39-6
3-[5-(4-cyclopropylphenyl)-1-methyl-1H-pyrazol-4-yl]-4-(3-fluoroazetidin-1-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / water; tetrahydrofuran / 18 h / 20 °C

2: tricyclohexylphosphine; potassium phosphate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane; water / 1.5 h / 150 °C

3: potassium carbonate / palladium diacetate / 1,4-dioxane / 48 h / 100 °C

With potassium phosphate; sodium hydrogencarbonate; potassium carbonate; tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium diacetate; In tetrahydrofuran; 1,4-dioxane; water;