Hesperetin 7-glucoside

Base Information

• Chemical Name: Hesperetin 7-glucoside
• CAS No.: 2500-68-7
• Molecular Formula: C₂₂H₂₄O₁₁
• Molecular Weight: 464.426
• Wikidata: Q104909771
• Mol file: 2500-68-7.mol

Synonyms:Hesperetin 7-glucoside;Glucohesperetin;SCHEMBL6525224;SCHEMBL24269009;LMPK12140378

Chemical Property of Hesperetin 7-glucoside

Chemical Property:

• XLogP3: 0.6
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 5
• Exact Mass: 464.13186158
• Heavy Atom Count: 33
• Complexity: 677

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O

Technology Process of Hesperetin 7-glucoside

There total 7 articles about Hesperetin 7-glucoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone (520-33-2,41001-90-5,69097-99-0) → (±)-hesperetin 7'-O-α-D-glucopyranoside (2500-68-7,31712-49-9,56086-32-9,67337-82-0)

Guidance literature:

With cyclodextrin glucanotransferase from Thermoanaerobacter sp.; soluble starch; In diethylene glycol dimethyl ether; acetonitrile; for 24h; pH=5; regioselective reaction;

DOI:10.3390/molecules23112285

Reference yield:

hesperidin → 5,7,3'-trihydroxy-4'-methoxyl flavanone 7-O-glucoside (2500-68-7,31712-49-9,56086-32-9,67337-82-0)

Guidance literature:

With sodium hydroxide; aspartate buffer; hesperidinase; at 42 ℃; for 0.5h; pH=3.8;

DOI:10.1016/S0031-9422(00)84502-1

Reference yield:

hesperidin (520-26-3) → 5,7,3'-trihydroxy-4'-methoxyl flavanone 7-O-glucoside (2500-68-7,31712-49-9,56086-32-9,67337-82-0)

Guidance literature:

With formic acid; cyclohexanol;

DOI:10.1021/ja01106a507

upstream raw materials:

hesperidin

(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone

Downstream raw materials:

(S)-5-acetoxy-2-(3-acetoxy-4-methoxy-phenyl)-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)-chroman-4-one