2-(4'-oxoretinylidene)-dimedone

Base Information

• Chemical Name: 2-(4'-oxoretinylidene)-dimedone
• CAS No.: 76686-03-8
• Molecular Formula: C₂₈H₃₆O₃
• Molecular Weight: 420.592
• Mol file: 76686-03-8.mol

Synonyms:

Chemical Property of 2-(4'-oxoretinylidene)-dimedone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4'-oxoretinylidene)-dimedone

There total 3 articles about 2-(4'-oxoretinylidene)-dimedone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

2-(4'-hydroxyretinylidene)-dimedone (76686-02-7) → 2-(4'-oxoretinylidene)-dimedone (76686-03-8)

Guidance literature:

With dipyridinium dichromate; pyridinium trifluroacetate; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1002/hlca.19800630606

Reference yield:

4-hydroxy-all-trans-retinal (18344-42-8) → 2-(4'-oxoretinylidene)-dimedone (76686-03-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 120 mg / piperidine / benzene / 4 h / Ambient temperature

2: 17 percent / pyridinium dichromate, pyridinium trifluoroacetate / CH₂Cl₂ / 2 h / Ambient temperature

With piperidine; dipyridinium dichromate; pyridinium trifluroacetate; In dichloromethane; benzene;

DOI:10.1002/hlca.19800630606

Reference yield:

all-trans 4-acetoxyretinal (76686-06-1,88424-96-8) → 2-(4'-oxoretinylidene)-dimedone (76686-03-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 10percent KOH / methanol / 2 h / Ambient temperature

2: 120 mg / piperidine / benzene / 4 h / Ambient temperature

3: 17 percent / pyridinium dichromate, pyridinium trifluoroacetate / CH₂Cl₂ / 2 h / Ambient temperature

With piperidine; potassium hydroxide; dipyridinium dichromate; pyridinium trifluroacetate; In methanol; dichloromethane; benzene;

DOI:10.1002/hlca.19800630606

upstream raw materials:

2-(4'-hydroxyretinylidene)-dimedone

4-hydroxy-all-trans-retinal

all-trans 4-acetoxyretinal

Downstream raw materials:

4-keto-all-trans-retinal

Refernces