(S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

Base Information

Chemical Name:(S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester
CAS No.:129145-19-3
Molecular Formula:C₄₅H₆₄N₆O₁₄
Molecular Weight:913.035
Hs Code.:

(S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

Synonyms:

Suppliers and Price of (S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

There total 3 articles about (S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 129145-15-9
(S)-6-[(R)-4-((S)-2-Benzyloxycarbonylamino-propionylamino)-4-carbamoyl-butyrylamino]-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

: 129145-19-3
(S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C

2: 1.) N-methylmorpholine (NMM), isobutylchloroformate / 1.) DMF, -15 deg C, 2 min, 2.) a) -15 deg C, 3 h, b) overnight

With 4-methyl-morpholine; hydrogen; isobutyl chloroformate; palladium on activated charcoal;

Reference yield:

: (S)-6-((R)-4-Amino-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

: 129145-19-3
(S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) N-methylmorpholine (NMM), isobutylchloroformate / 1.) DMF, -15 deg C, 2.) a) -15 deg C, 2 h, b) overnight

2: H₂ / 10percent Pd/C

3: 1.) N-methylmorpholine (NMM), isobutylchloroformate / 1.) DMF, -15 deg C, 2 min, 2.) a) -15 deg C, 3 h, b) overnight

With 4-methyl-morpholine; hydrogen; isobutyl chloroformate; palladium on activated charcoal;

Reference yield:

: (S)-6-[(R)-4-((S)-2-Amino-propionylamino)-4-carbamoyl-butyrylamino]-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

: 2862-03-5
Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside

: 129145-19-3
(S)-6-((R)-4-{(S)-2-[(R)-2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester

Guidance literature:: With 4-methyl-morpholine; isobutyl chloroformate; Yield given. Multistep reaction; 1.) DMF, -15 deg C, 2 min, 2.) a) -15 deg C, 3 h, b) overnight;