3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine

Base Information

Chemical Name:3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine
CAS No.:86808-65-3
Molecular Formula:C₂₂H₂₀O₂S
Molecular Weight:348.466
Hs Code.:

3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzo<b,f>thiepine

Synonyms:

Suppliers and Price of 3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine

There total 7 articles about 3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51723-75-2
7-methoxydibenzothiepin-10(11H)-one

: 86808-65-3
3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / tetrabutylammonium hydrogen sulfate, aq. NaOH / CH₂Cl₂ / 0.5 h

2: 1.) BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, RT, 18 h

With sodium hydroxide; n-butyllithium; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane;
DOI:10.1021/jm00362a009

Reference yield:

: 50900-42-0
2-(3-methoxyphenylthio)benzyl alcohol

: 86808-65-3
3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / toluene / 1 h / 80 °C

2: ethanol; H₂O / 12 h / Heating

3: aq. KOH / ethanol / 3 h / Heating

4: polyphosphoric acid / toluene / 4 h / Heating

5: 62 percent / tetrabutylammonium hydrogen sulfate, aq. NaOH / CH₂Cl₂ / 0.5 h

6: 1.) BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, RT, 18 h

With potassium hydroxide; sodium hydroxide; n-butyllithium; thionyl chloride; PPA; tetra(n-butyl)ammonium hydrogensulfate; In ethanol; dichloromethane; water; toluene;
DOI:10.1021/jm00362a009

Reference yield:

: 51723-74-1
<2-(3-methoxyphenylthio)phenyl>acetic acid

: 86808-65-3
3-methoxy-10-methyl-11-phenyl-11-hydroxy-10,11-dihydrodibenzothiepine

Guidance literature:: Multi-step reaction with 3 steps

1: polyphosphoric acid / toluene / 4 h / Heating

2: 62 percent / tetrabutylammonium hydrogen sulfate, aq. NaOH / CH₂Cl₂ / 0.5 h

3: 1.) BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, RT, 18 h

With sodium hydroxide; n-butyllithium; PPA; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; toluene;
DOI:10.1021/jm00362a009