8-dehydrocurcuhydroquinone dimethyl ether

Base Information

• Chemical Name: 8-dehydrocurcuhydroquinone dimethyl ether
• CAS No.: 78919-98-9
• Molecular Formula: C₁₇H₂₄O₂
• Molecular Weight: 260.376
• Mol file: 78919-98-9.mol

Synonyms:

Chemical Property of 8-dehydrocurcuhydroquinone dimethyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-dehydrocurcuhydroquinone dimethyl ether

There total 3 articles about 8-dehydrocurcuhydroquinone dimethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-Methyl-hept-5-en-2-on (110-93-0,129085-68-3) → 8-dehydrocurcuhydroquinone dimethyl ether (78919-98-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) Mg, 1,2-dibromoethane / 1) THF, reflux, 30 min, 2) reflux, 30 min

2: Amberlyst-15 / benzene / 36 h / Ambient temperature

With amberlyst-15; magnesium; ethylene dibromide; In benzene;

DOI:10.1021/jo00336a006

Reference yield:

1-bromo-2,5-dimethoxy-4-methylbenzene (13321-74-9) → 8-dehydrocurcuhydroquinone dimethyl ether (78919-98-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) Mg, 1,2-dibromoethane / 1) THF, reflux, 30 min, 2) reflux, 30 min

2: Amberlyst-15 / benzene / 36 h / Ambient temperature

With amberlyst-15; magnesium; ethylene dibromide; In benzene;

DOI:10.1021/jo00336a006

Reference yield:

2-(2,5-dimethoxy-4-methylphenyl)-6-methylhept-5-en-2-ol (78919-97-8) → 8-dehydrocurcuhydroquinone dimethyl ether (78919-98-9) + 8(10)-dehydrocurcuhydroquinone dimethyl ether (78919-99-0)

Guidance literature:

With amberlyst-15; In benzene; for 36h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00336a006

upstream raw materials:

2-(2,5-dimethoxy-4-methylphenyl)-6-methylhept-5-en-2-ol

6-Methyl-hept-5-en-2-on

1-bromo-2,5-dimethoxy-4-methylbenzene