6beta,19-Epoxypregn-4-ene-3,20-dione

Base Information

Chemical Name:6beta,19-Epoxypregn-4-ene-3,20-dione
CAS No.:2205-86-9
Molecular Formula:C₂₁H₂₈O₃
Molecular Weight:328.452
Hs Code.:
Nikkaji Number:J662.262C
Wikidata:Q27148770

Synonyms:6beta,19-Epoxypregn-4-ene-3,20-dione;(1S,2S,5S,6S,9S,10S,12R)-6-acetyl-5-methyl-19-oxapentacyclo[10.5.2.01,13.02,10.05,9]nonadec-13-en-15-one;CHEBI:79648;Q27148770

Suppliers and Price of 6beta,19-Epoxypregn-4-ene-3,20-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6beta,19-Epoxypregn-4-ene-3,20-dione

Chemical Property:

Vapor Pressure:6.98E-10mmHg at 25°C
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:328.20384475
Heavy Atom Count:24
Complexity:650

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(CCC3C2CC4C5=CC(=O)CCC35CO4)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H]4C5=CC(=O)CC[C@]35CO4)C

Technology Process of 6beta,19-Epoxypregn-4-ene-3,20-dione

There total 9 articles about 6beta,19-Epoxypregn-4-ene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5490-69-7
5α-bromo-6β,19-epoxypregnan-3,20-dione

: 2205-86-9
6β,19-epoxypregn-4-en-3,20-dione

Guidance literature:: With potassium acetate; In methanol; Reflux;
DOI:10.1007/s11172-021-3337-6

Reference yield:

: 145-13-1
Pregnenolone

: 2205-86-9
6β,19-epoxypregn-4-en-3,20-dione

Guidance literature:: Multi-step reaction with 6 steps

1: 99 percent / pyridine / 60 h / Ambient temperature

2: 75 percent / N-bromoacetamide, 70percent perchloric acid, water / dioxane / 0.5 h / Ambient temperature

3: 81 percent / lead tetraacetate, iodine / benzene / 1 h / Heating; Irradiation

4: 77 percent / K₂CO₃, methanol / 2.5 h / Ambient temperature

5: 8 N chromic acid / acetone / 0.33 h / Ambient temperature

6: Li₂CO₃, LiBr / dimethylformamide / 0.5 h / Heating

With pyridine; lead(IV) acetate; methanol; perchloric acid; water; iodine; chromic acid; lithium carbonate; potassium carbonate; lithium bromide; N-bromoacetamide; In 1,4-dioxane; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1007/BF00630435

Reference yield:

: 1778-02-5
Pregnenolone acetate

: 2205-86-9
6β,19-epoxypregn-4-en-3,20-dione

Guidance literature:: Multi-step reaction with 5 steps

1: 75 percent / N-bromoacetamide, 70percent perchloric acid, water / dioxane / 0.5 h / Ambient temperature

2: 81 percent / lead tetraacetate, iodine / benzene / 1 h / Heating; Irradiation

3: 77 percent / K₂CO₃, methanol / 2.5 h / Ambient temperature

4: 8 N chromic acid / acetone / 0.33 h / Ambient temperature

5: Li₂CO₃, LiBr / dimethylformamide / 0.5 h / Heating

With lead(IV) acetate; methanol; perchloric acid; water; iodine; chromic acid; lithium carbonate; potassium carbonate; lithium bromide; N-bromoacetamide; In 1,4-dioxane; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1007/BF00630435