endo-2,exo-6-Dihyhydroxycineol

Base Information

• Chemical Name: endo-2,exo-6-Dihyhydroxycineol
• CAS No.: 20178-12-5
• Molecular Formula: C₁₀H₁₈O₃
• Molecular Weight: 186.251
• Mol file: 20178-12-5.mol

Synonyms:

Chemical Property of endo-2,exo-6-Dihyhydroxycineol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of endo-2,exo-6-Dihyhydroxycineol

There total 6 articles about endo-2,exo-6-Dihyhydroxycineol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(1R,4R)-2,6,6-trimethyl-7-oxabicyclo[3.2.1]oct-2-ene (55822-06-5) → 1,8-epoxy-p-menthane-2,6-diol (20178-12-5,32221-11-7,38223-98-2,38235-66-4,56084-15-2)

Guidance literature:

With formic acid; dihydrogen peroxide; at 40 - 45 ℃;

Reference yield:

trans-sobrerol (38235-58-4) → 1,8-epoxy-p-menthane-2,6-diol (20178-12-5,32221-11-7,38223-98-2,38235-66-4,56084-15-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 5percent aq. H₂SO₄

2: 85 percent / 30percent aq. H₂O₂, formic acid / 40 - 45 °C

With formic acid; sulfuric acid; dihydrogen peroxide;

Reference yield:

→ (1S,2R,4R,6S)-2,6-dihydroxy-1,8-cineole (20178-12-5,32221-11-7,38223-98-2,38235-66-4,56084-15-2)

Guidance literature:

aus dem Dibromid (6) und Pb(OH)2;

DOI:10.1016/S0040-4020(01)92470-6

upstream raw materials:

(1R,4R)-2,6,6-trimethyl-7-oxabicyclo[3.2.1]oct-2-ene

trans-sobrerol

Refernces