(S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

Base Information

Chemical Name:(S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide
CAS No.:97731-64-1
Molecular Formula:C₃₉H₅₅N₉O₈S₂
Molecular Weight:842.053
Hs Code.:

(S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

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Suppliers and Price of (S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

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Chemical Property of (S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

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Technology Process of (S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

There total 4 articles about (S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 97731-65-2
[(S)-1-((4R,7S,13S,16S,19R)-13,16-Dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-ylcarbamoyl)-3-dimethylcarbamoyl-propyl]-carbamic acid tert-butyl ester

: 97731-64-1
(S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;
DOI:10.1021/jm00148a029

Reference yield:

: 97731-62-9
(4R,7S,13S,16S,19R)-19-Amino-13,16-dibenzyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicosane-4-carboxylic acid amide

: 97731-64-1
(S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / 1-hydroxybenzotriazole (HOBt), dicyclohexylcarbodiimide (DCC), N-methylmorpholine (NMM) / dimethylformamide / 48 h / Ambient temperature

2: 40 mg / 4N aq. HCl / dioxane / 1 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm00148a029

Reference yield:

: 97731-63-0
((4R,7S,13S,16S,19R)-13,16-Dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-carbamic acid tert-butyl ester

: 97731-64-1
(S)-2-Amino-pentanedioic acid 1-[((4R,7S,13S,16S,19R)-13,16-dibenzyl-4-carbamoyl-7-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-19-yl)-amide] 5-dimethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 255 mg / 98percent formic acid / 1.5 h / Ambient temperature

2: 59 percent / 1-hydroxybenzotriazole (HOBt), dicyclohexylcarbodiimide (DCC), N-methylmorpholine (NMM) / dimethylformamide / 48 h / Ambient temperature

3: 40 mg / 4N aq. HCl / dioxane / 1 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; formic acid; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm00148a029