S-α-phenylethylamide of α-(N-dimethylcarbamoylaminooxy)isobutyric acid

Base Information

• Chemical Name: S-α-phenylethylamide of α-(N-dimethylcarbamoylaminooxy)isobutyric acid
• CAS No.: 121410-35-3
• Molecular Formula: C₁₅H₂₃N₃O₃
• Molecular Weight: 293.366
• Mol file: 121410-35-3.mol

Synonyms:

Chemical Property of S-α-phenylethylamide of α-(N-dimethylcarbamoylaminooxy)isobutyric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-α-phenylethylamide of α-(N-dimethylcarbamoylaminooxy)isobutyric acid

There total 4 articles about S-α-phenylethylamide of α-(N-dimethylcarbamoylaminooxy)isobutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-phenyl-ethylamine (2627-86-3) → C15H23N3O3 (121410-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) KOH, 2.) SOCl₂ / 1.) MeOH, 2.) 20 - 40 deg C, 3.5 h, 3.) CHCl₃

2: Et₃N / acetonitrile / 1.) 20 deg C, 3 d, 2.) reflux, 7 h

With potassium hydroxide; thionyl chloride; triethylamine; In acetonitrile;

DOI:10.1007/BF00952630

Reference yield:

(S)-1-phenyl-ethylamine (2627-86-3) → S-α-phenylethylamide of α-(N-dimethylcarbamoylaminooxy)isobutyric acid (121410-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) KOH, 2.) SOCl₂ / 1.) MeOH, 2.) 20 - 40 deg C, 3.5 h, 3.) CHCl₃

2: Et₃N / acetonitrile / 1.) 20 deg C, 3 d, 2.) reflux, 7 h

With potassium hydroxide; thionyl chloride; triethylamine; In acetonitrile;

DOI:10.1007/BF00952630

Reference yield:

S-α-phenylethylamide of α-aminooxyisobutyric acid (121410-34-2) + N,N-Dimethylcarbamoyl chloride (79-44-7) → C15H23N3O3 (121410-35-3) + S-α-phenylethylamide of α-(N-dimethylcarbamoylaminooxy)isobutyric acid (121410-35-3)

Guidance literature:

With triethylamine; In acetonitrile; Yield given. Title compound not separated from byproducts; 1.) 20 deg C, 3 d, 2.) reflux, 7 h;

DOI:10.1007/BF00952630

upstream raw materials:

S-α-phenylethylamide of α-aminooxyisobutyric acid

N,N-Dimethylcarbamoyl chloride

(S)-1-phenyl-ethylamine

Downstream raw materials:

S-α-phenylethylamide of α-(N-ethoxyaminooxy)isobutyric acid

C₁₄H₂₂N₂O₃

C₁₇H₂₇N₃O₄

S-α-phenylethylamide of α-(N-dimethylcarbamoyl-N-ethoxyaminooxy)isobutyric acid