α-trimethylsilylmethylphenylacetic acid

Base Information

Chemical Name:α-trimethylsilylmethylphenylacetic acid
CAS No.:129367-56-2
Molecular Formula:C₁₂H₁₈O₂Si
Molecular Weight:222.359
Hs Code.:

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Suppliers and Price of α-trimethylsilylmethylphenylacetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of α-trimethylsilylmethylphenylacetic acid

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Technology Process of α-trimethylsilylmethylphenylacetic acid

There total 4 articles about α-trimethylsilylmethylphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-phenyl-N-(quinolin-8-yl)propanamide

: 129367-56-2
α-trimethylsilylmethylphenylacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate; lithium acetate; palladium diacetate; silver carbonate / toluene / 125 °C / Sealed tube

2: dmap / 30 h / Inert atmosphere; Reflux

3: sodium hydroxide; water / 20 h / 120 °C / Sealed tube

With dmap; lithium acetate; water; palladium diacetate; sodium hydrogencarbonate; silver carbonate; sodium hydroxide; In toluene;
DOI:10.1002/anie.201607766

Reference yield:

: C₂₆H₂₅N₃OPd

: 129367-56-2
α-trimethylsilylmethylphenylacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate; lithium acetate; silver carbonate / toluene / 10 h / 125 °C / Sealed tube

2: dmap / 30 h / Inert atmosphere; Reflux

3: sodium hydroxide; water / 20 h / 120 °C / Sealed tube

With dmap; lithium acetate; water; sodium hydrogencarbonate; silver carbonate; sodium hydroxide; In toluene;
DOI:10.1002/anie.201607766