C₁₈H₂₁NO₂

Base Information

• Chemical Name: C₁₈H₂₁NO₂
• CAS No.: 1182178-68-2
• Molecular Formula: C₁₈H₂₁NO₂
• Molecular Weight: 283.37
• Mol file: 1182178-68-2.mol

Synonyms:

Chemical Property of C₁₈H₂₁NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₁NO₂

There total 8 articles about C₁₈H₂₁NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H21NO2 (1182178-49-9,1182718-45-1,1182718-48-4) → C18H21NO2 (1182178-68-2,1182178-72-8) + C19H21NO2 + C19H21NO2

Guidance literature:

Multi-step reaction with 2 steps

1: CHIRACEL_.(R). OD-H / hexane; isopropyl alcohol / Resolution of racemate

2: chloroform / 6 h / -40 °C / Inert atmosphere; Irradiation

With CHIRACEL OD-H; In hexane; chloroform; isopropyl alcohol;

DOI:10.1021/ja9050586

Reference yield:

2-(1,1-dimethylethyl)-benzenamine (6310-21-0) → C18H21NO2 (1182178-68-2,1182178-72-8) + C19H21NO2 + C19H21NO2

Guidance literature:

Multi-step reaction with 5 steps

1: ethanol / 80 °C / Inert atmosphere

2: sodium tetrahydroborate / dimethyl sulfoxide / Inert atmosphere; Reflux

3: sodium carbonate / dichloromethane / 20 - 23 °C / Inert atmosphere

4: CHIRACEL_.(R). OD-H / hexane; isopropyl alcohol / Resolution of racemate

5: chloroform / 6 h / -40 °C / Inert atmosphere; Irradiation

With sodium tetrahydroborate; sodium carbonate; In ethanol; hexane; dichloromethane; chloroform; dimethyl sulfoxide; isopropyl alcohol;

DOI:10.1021/ja9050586

Reference yield:

phenylglyoxylyl chloride (25726-04-9) → C18H21NO2 (1182178-68-2,1182178-72-8) + C19H21NO2 + C19H21NO2

Guidance literature:

Multi-step reaction with 3 steps

1: sodium carbonate / dichloromethane / 20 - 23 °C / Inert atmosphere

2: CHIRACEL_.(R). OD-H / hexane; isopropyl alcohol / Resolution of racemate

3: chloroform / 6 h / -40 °C / Inert atmosphere; Irradiation

With sodium carbonate; In hexane; dichloromethane; chloroform; isopropyl alcohol;

DOI:10.1021/ja9050586

upstream raw materials:

phenylglyoxylyl chloride

C₁₅H₂₀N₂O₂

C₁₉H₂₁NO₂

2-(1,1-dimethylethyl)-benzenamine