C₂₉H₃₉ClN₄O₂*C₄H₄O₄

Base Information

• Chemical Name: C₂₉H₃₉ClN₄O₂*C₄H₄O₄
• CAS No.: 1263197-07-4
• Molecular Formula: C₄H₄O₄*C₂₉H₃₉ClN₄O₂
• Molecular Weight: 627.181
• Mol file: 1263197-07-4.mol

Synonyms:

Chemical Property of C₂₉H₃₉ClN₄O₂*C₄H₄O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₉ClN₄O₂*C₄H₄O₄

There total 11 articles about C₂₉H₃₉ClN₄O₂*C₄H₄O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H26N2O6 (1415413-38-5) → C29H39ClN4O2*C4H4O4 (1263197-07-4)

Guidance literature:

Multi-step reaction with 15 steps

1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

2: triethylamine / dichloromethane / 1 h / 20 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; morpholine / tetrahydrofuran / 1 h / 20 °C

4: dichloromethane / 2 h / 20 °C

5: N-chloro-succinimide / dichloromethane / 2 h / 20 °C

6: 18 h / 60 °C

7: hydrogenchloride / dichloromethane; water / 4 h / 40 °C

8: thionyl chloride / 1 h / 20 °C

9: acetic acid / toluene / 2 h / 110 °C

10: sodium cyanoborohydride / 6 h / 20 °C

11: triethylamine / dichloromethane / 5 h / 0 - 40 °C

12: sodium hydroxide; water / methanol / 0.5 h / 50 °C

13: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C

14: thiophenol; caesium carbonate / acetonitrile / 1.5 h / 20 °C

15: methanol / 0.02 h / 20 °C

With morpholine; hydrogenchloride; N-chloro-succinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; thionyl chloride; water; sodium cyanoborohydride; caesium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; thiophenol; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;

DOI:10.1016/j.bmcl.2012.09.103

Reference yield:

C11H18N2O4 → C29H39ClN4O2*C4H4O4 (1263197-07-4)

Guidance literature:

Multi-step reaction with 14 steps

1: triethylamine / dichloromethane / 1 h / 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; morpholine / tetrahydrofuran / 1 h / 20 °C

3: dichloromethane / 2 h / 20 °C

4: N-chloro-succinimide / dichloromethane / 2 h / 20 °C

5: 18 h / 60 °C

6: hydrogenchloride / dichloromethane; water / 4 h / 40 °C

7: thionyl chloride / 1 h / 20 °C

8: acetic acid / toluene / 2 h / 110 °C

9: sodium cyanoborohydride / 6 h / 20 °C

10: triethylamine / dichloromethane / 5 h / 0 - 40 °C

11: sodium hydroxide; water / methanol / 0.5 h / 50 °C

12: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C

13: thiophenol; caesium carbonate / acetonitrile / 1.5 h / 20 °C

14: methanol / 0.02 h / 20 °C

With morpholine; hydrogenchloride; N-chloro-succinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; thionyl chloride; water; sodium cyanoborohydride; caesium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; thiophenol; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;

DOI:10.1016/j.bmcl.2012.09.103

Reference yield:

C17H21N3O8S (1415413-39-6) → C29H39ClN4O2*C4H4O4 (1263197-07-4)

Guidance literature:

Multi-step reaction with 13 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; morpholine / tetrahydrofuran / 1 h / 20 °C

2: dichloromethane / 2 h / 20 °C

3: N-chloro-succinimide / dichloromethane / 2 h / 20 °C

4: 18 h / 60 °C

5: hydrogenchloride / dichloromethane; water / 4 h / 40 °C

6: thionyl chloride / 1 h / 20 °C

7: acetic acid / toluene / 2 h / 110 °C

8: sodium cyanoborohydride / 6 h / 20 °C

9: triethylamine / dichloromethane / 5 h / 0 - 40 °C

10: sodium hydroxide; water / methanol / 0.5 h / 50 °C

11: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C

12: thiophenol; caesium carbonate / acetonitrile / 1.5 h / 20 °C

13: methanol / 0.02 h / 20 °C

With morpholine; hydrogenchloride; N-chloro-succinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; thionyl chloride; water; sodium cyanoborohydride; caesium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; thiophenol; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;

DOI:10.1016/j.bmcl.2012.09.103

upstream raw materials:

C₁₆H₂₆N₂O₆

C₁₇H₂₁N₃O₈S

C₁₃H₁₇N₃O₆S

C₁₉H₂₉N₃O₈S