demethylacrovestone

Base Information

• Chemical Name: demethylacrovestone
• CAS No.: 135383-99-2
• Molecular Formula: C₃₁H₄₀O₈
• Molecular Weight: 540.654
• Mol file: 135383-99-2.mol

Synonyms:

Chemical Property of demethylacrovestone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of demethylacrovestone

There total 2 articles about demethylacrovestone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone (27364-71-2) + isovaleraldehyde (590-86-3) → demethylacrovestone (135383-99-2)

Guidance literature:

2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone; isovaleraldehyde; With aluminum (III) chloride; In toluene; at 111 ℃; for 1.5h; Microwave irradiation;

DOI:10.1021/acs.jnatprod.6b01008

Reference yield:

2-methyl-3-buten-2-ol (115-18-4) + 2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) → demethylacrovestone (135383-99-2)

Guidance literature:

Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / 1,4-dioxane / 12 h / 20 °C

2: aluminum (III) chloride / toluene / 1.5 h / 111 °C / Microwave irradiation

With aluminum (III) chloride; boron trifluoride diethyl etherate; In 1,4-dioxane; toluene; 2: |Friedel-Crafts Alkylation / 2: |Friedel-Crafts Alkylation;

DOI:10.1021/acs.jnatprod.6b01008

upstream raw materials:

2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone

isovaleraldehyde

2-methyl-3-buten-2-ol

2,4,6-trihydroxyacetophenone