p-Isothiocyanatophenyl urethane

Base Information

• Chemical Name: p-Isothiocyanatophenyl urethane
• CAS No.: 78889-13-1
• Molecular Formula: C₁₀H₁₀N₂O₂S
• Molecular Weight: 222.268
• Mol file: 78889-13-1.mol

Synonyms:

Chemical Property of p-Isothiocyanatophenyl urethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-Isothiocyanatophenyl urethane

There total 1 articles about p-Isothiocyanatophenyl urethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiophosgene (463-71-8) + N-(4-aminophenyl)carbamic acid ethyl ester (57399-97-0) → p-Isothiocyanatophenyl urethane (78889-13-1)

Guidance literature:

In 1,4-dioxane; water; 1.) 15 deg C , 2 h , 2.) RT , overnight;

Reference yield:

p-Isothiocyanatophenyl urethane (78889-13-1) → Amoscanate (26328-53-0,100990-46-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 0.8 g / PCl₅ / chlorobenzene / 2 h / Heating

2: 6.7 g / Pyridine / benzene / 3 h / 50 - 60 °C

3: 0.1 g / anhydrous K₂CO₃ / nitrobenzene / 3 h / 190 °C / Further catalysts

With pyridine; phosphorus pentachloride; potassium carbonate; In nitrobenzene; chlorobenzene; benzene;

Reference yield:

p-Isothiocyanatophenyl urethane (78889-13-1) → (4-Isothiocyanato-phenyl)-carbamic acid 4-nitro-phenyl ester (78889-14-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.8 g / PCl₅ / chlorobenzene / 2 h / Heating

2: 6.7 g / Pyridine / benzene / 3 h / 50 - 60 °C

With pyridine; phosphorus pentachloride; In chlorobenzene; benzene;

upstream raw materials:

thiophosgene

N-(4-aminophenyl)carbamic acid ethyl ester

Downstream raw materials:

(4-Isothiocyanato-phenyl)-carbamic acid 4-nitro-phenyl ester

Amoscanate