benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol

Base Information

• Chemical Name: benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol
• CAS No.: 138524-42-2
• Molecular Formula: C₁₇H₂₈O₃
• Molecular Weight: 280.408
• Mol file: 138524-42-2.mol

Synonyms:

Chemical Property of benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol

There total 6 articles about benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

benzyl ether of 3(S),7-dimethyl-6-(R,S)-7-epoxyoctan-1-ol → benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol (138524-36-4,138524-42-2)

Guidance literature:

With perchloric acid; In tetrahydrofuran; water; at 20 ℃; for 2h;

DOI:10.1007/BF00963502

Reference yield:

(S)-((3,7-dimethyloct-6-enyloxy)methyl)benzene (84237-05-8) → benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol (138524-36-4,138524-42-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent / N-bromosuuccinimide, NaHCO₃ / dimethylsulfoxide; H₂O / 1 h / -5 - 0 °C

2: 96 percent / K₂CO₃ / ethanol / 0.33 h / 20 °C

3: 82 percent / HClO₄ / tetrahydrofuran; H₂O / 2 h / 20 °C

With N-Bromosuccinimide; perchloric acid; sodium hydrogencarbonate; potassium carbonate; In tetrahydrofuran; ethanol; water; dimethyl sulfoxide;

DOI:10.1007/BF00963502

Reference yield:

benzyl ether of 6(R,S)-bromo-7-hydroxy-3(S),7-dimethyloctan-1-ol (67245-13-0,138524-34-2,138524-40-0) → benzyl ether of 3(S),7-dimethyloctane-1,6-(R,S)-7-triol (138524-36-4,138524-42-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / K₂CO₃ / ethanol / 0.33 h / 20 °C

2: 82 percent / HClO₄ / tetrahydrofuran; H₂O / 2 h / 20 °C

With perchloric acid; potassium carbonate; In tetrahydrofuran; ethanol; water;

DOI:10.1007/BF00963502

upstream raw materials:

(S)-((3,7-dimethyloct-6-enyloxy)methyl)benzene

benzyl ether of 6(R,S)-bromo-7-hydroxy-3(S),7-dimethyloctan-1-ol

benzyl chloride

(S)-3,7-dimethyl-6-octen-1-ol

Downstream raw materials:

(S)-6-benzyloxy-4-methylhexanal

bbenzyl ether of 3(S),7,11,15,19,23,27,31-octamethylditriaconta-6Z,10Z,14Z,18E,22E,26E,30-heptaen-1-ol

benzyl ether of 7-hydroxymethyl-3(S),11,15,19,23,27,31-heptamethylditriaconta-6E,10Z,14Z,18Z,22E,26E,30-heptaen-1-ol

benzyl ether of 3(S),11,15,19,23,27,31-heptamethyl-7-formylditriaconta-6E,10Z-14Z,18E,22E,26E,30-heptaen-1-ol