C₅₁H₇₇N₁₅O₁₁S

Base Information

• Chemical Name: C₅₁H₇₇N₁₅O₁₁S
• CAS No.: 1269631-37-9
• Molecular Formula: C₅₁H₇₇N₁₅O₁₁S
• Molecular Weight: 1108.33
• Mol file: 1269631-37-9.mol

Synonyms:

Chemical Property of C₅₁H₇₇N₁₅O₁₁S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₁H₇₇N₁₅O₁₁S

There total 6 articles about C₅₁H₇₇N₁₅O₁₁S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-methyl 3-(4-(2-bromoethoxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoate (1269631-36-8) → C51H77N15O11S (1269631-37-9)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium iodide / acetone / 6 h / Reflux

2: water; lithium hydroxide / tetrahydrofuran / 3 h / 0 °C

3: trifluoroacetic acid

4: E_.coli tRNA phenylalanine; wild-type L/F-transferase; N-(3-aminopropyl)-1,4-diaminobutane; potassium chloride; ATP; magnesium chloride; diothiothreitol / 5 h / 37 °C / aq. buffer; Darkness

With N-(3-aminopropyl)-1,4-diaminobutane; E_.coli tRNA phenylalanine; wild-type L/F-transferase; potassium chloride; water; ATP; trifluoroacetic acid; sodium iodide; magnesium chloride; lithium hydroxide; diothiothreitol; In tetrahydrofuran; acetone;

DOI:10.1039/c1cc12196k

Reference yield:

(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester (4326-36-7) → C51H77N15O11S (1269631-37-9)

Guidance literature:

Multi-step reaction with 5 steps

1: sodium methylate / acetonitrile / 12 h / Reflux

2: sodium iodide / acetone / 6 h / Reflux

3: water; lithium hydroxide / tetrahydrofuran / 3 h / 0 °C

4: trifluoroacetic acid

5: E_.coli tRNA phenylalanine; wild-type L/F-transferase; N-(3-aminopropyl)-1,4-diaminobutane; potassium chloride; ATP; magnesium chloride; diothiothreitol / 5 h / 37 °C / aq. buffer; Darkness

With N-(3-aminopropyl)-1,4-diaminobutane; E_.coli tRNA phenylalanine; wild-type L/F-transferase; potassium chloride; water; sodium methylate; ATP; trifluoroacetic acid; sodium iodide; magnesium chloride; lithium hydroxide; diothiothreitol; In tetrahydrofuran; acetone; acetonitrile;

DOI:10.1039/c1cc12196k

Reference yield:

C17H24INO5 (1333069-58-1) → C51H77N15O11S (1269631-37-9)

Guidance literature:

Multi-step reaction with 3 steps

1: water; lithium hydroxide / tetrahydrofuran / 3 h / 0 °C

2: trifluoroacetic acid

3: E_.coli tRNA phenylalanine; wild-type L/F-transferase; N-(3-aminopropyl)-1,4-diaminobutane; potassium chloride; ATP; magnesium chloride; diothiothreitol / 5 h / 37 °C / aq. buffer; Darkness

With N-(3-aminopropyl)-1,4-diaminobutane; E_.coli tRNA phenylalanine; wild-type L/F-transferase; potassium chloride; water; ATP; trifluoroacetic acid; magnesium chloride; lithium hydroxide; diothiothreitol; In tetrahydrofuran;

DOI:10.1039/c1cc12196k

upstream raw materials:

4-(2-bromoethoxy)phenylalanine

RGPCRAFI

C₁₇H₂₄INO₅

O-(2-iodoethyl)-L-tyrosine