2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl tricyclo[3.3.1.1~3,7~]decane-1-carboxylate

Base Information

• Chemical Name: 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl tricyclo[3.3.1.1~3,7~]decane-1-carboxylate
• CAS No.: 17231-42-4
• Molecular Formula: C₃₃H₄₀F₃N₃O₂S
• Molecular Weight: 599.761
• Mol file: 17231-42-4.mol

Synonyms:1-Adamantanecarboxylicacid,2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethylester (8CI); 1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-, 1-adamantanecarboxylate(ester); NSC 292593

Chemical Property of 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl tricyclo[3.3.1.1~3,7~]decane-1-carboxylate

Chemical Property:

• Vapor Pressure: 1.89E-18mmHg at 25°C
• Boiling Point: 681.9°C at 760 mmHg
• Flash Point: 366.2°C
• Density: 1.267g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl tricyclo[3.3.1.1~3,7~]decane-1-carboxylate

There total 2 articles about 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl tricyclo[3.3.1.1~3,7~]decane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Adamantanecarbonyl chloride (2094-72-6) + Fluphenazine (69-23-8) → adamantane-1-carboxylic acid 2-{4-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethyl ester (17231-42-4)

Guidance literature:

With triethylamine; In benzene; for 18h; Heating;

DOI:10.1021/jm00212a023

Reference yield:

→ adamantane-1-carboxylic acid 2-{4-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethyl ester (17231-42-4)

Guidance literature:

<(Trifluoromethyl-2-phenothiazinyl-10)propyl-3>-4-piperazin-1-ethanol, Adaman- toyl-1-chlorid;

upstream raw materials:

1-Adamantanecarbonyl chloride

Fluphenazine