(2E)-((Aminocarbonothioyl)hydrazono)acetic acid

Base Information

• Chemical Name: (2E)-((Aminocarbonothioyl)hydrazono)acetic acid
• CAS No.: 928-74-5
• Molecular Formula: C3H5 N3 O2 S
• Molecular Weight: 147.158
• NSC Number: 103752
• Mol file: 928-74-5.mol

Synonyms:928-74-5;(2E)-((Aminocarbonothioyl)hydrazono)acetic acid;(2E)-2-(carbamothioylhydrazinylidene)acetic acid;763901-34-4;2-(2-Carbamothioylhydrazono)acetic acid;(E)-2-(2-carbamothioylhydrazono)acetic acid;Acetic acid, [(aminothioxomethyl)hydrazono]-;Glyoxalic acid thiosemicarbazone;(2E)-2-[(carbamothioylamino)imino]acetic acid;NSC103752;MFCD00194073;MFCD06009416;STL194061;AKOS002252494;AKOS002352498;2-(2-Carbamothioylhydrazono)aceticacid;NSC-103752;BB 0218321;(2E)-(2-carbamothioylhydrazinylidene)ethanoic acid;F3249-0068

Chemical Property of (2E)-((Aminocarbonothioyl)hydrazono)acetic acid

Chemical Property:

• Vapor Pressure: 1.21E-05mmHg at 25°C
• Boiling Point: 344.1°C at 760 mmHg
• Flash Point: 161.9°C
• Density: 1.63g/cm³
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 147.01024758
• Heavy Atom Count: 9
• Complexity: 155

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=NNC(=S)N)C(=O)O
• Isomeric SMILES: C(=N/NC(=S)N)\C(=O)O

Technology Process of (2E)-((Aminocarbonothioyl)hydrazono)acetic acid

There total 2 articles about (2E)-((Aminocarbonothioyl)hydrazono)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

thiosemicarbazide (79-19-6) + Glyoxilic acid (298-12-4) → 2-[2-(aminothioxomethyl)hydrazinyl]acetic acid (928-74-5)

Guidance literature:

In water;

DOI:10.1515/znb-2006-0909

Reference yield:

→ 2-[2-(aminothioxomethyl)hydrazinyl]acetic acid (928-74-5)

Guidance literature:

Dichloressigsaeure, 1) KOH, 2) Thiosemicarbazid / KOAc;

Reference yield:

2-[2-(aminothioxomethyl)hydrazinyl]acetic acid (928-74-5) → 6-aza-2-thiouracil (626-08-4)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

thiosemicarbazide

Glyoxilic acid

Downstream raw materials:

6-aza-2-thiouracil