Technology Process of dimethyl 2-azidotriphenylmethane-4',4''-dicarboxylate
There total 6 articles about dimethyl 2-azidotriphenylmethane-4',4''-dicarboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 11.6 percent / tetrahydrofuran; toluene; diethyl ether / 1.) 0 deg C, 2 h, 2.) room temperature, overnight
2: 78 percent / N-bromosuccinimide / CCl4 / 2 h / Heating
3: 1.) conc. hydrochloric acid, 2.) dry hydrogen chloride / 1.) 95percent ethanol, 3 h, reflux, 2.) 18 h, reflux
4: 92 percent / red phosphorus, iodine / acetic acid; H2O / 4 h / Heating
5: 1.) 2N-sulphuric acid, sodium nitrite, 2.) sodium azide / 1.) 1,4-dioxan, water, -5 deg C, 30 min
With
hydrogenchloride; phosphorus; N-Bromosuccinimide; sodium azide; sulfuric acid; iodine; sodium nitrite;
In
tetrahydrofuran; tetrachloromethane; diethyl ether; water; acetic acid; toluene;
DOI:10.1039/P19810001132
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 11.6 percent / tetrahydrofuran; toluene; diethyl ether / 1.) 0 deg C, 2 h, 2.) room temperature, overnight
2: 78 percent / N-bromosuccinimide / CCl4 / 2 h / Heating
3: 1.) conc. hydrochloric acid, 2.) dry hydrogen chloride / 1.) 95percent ethanol, 3 h, reflux, 2.) 18 h, reflux
4: 92 percent / red phosphorus, iodine / acetic acid; H2O / 4 h / Heating
5: 1.) 2N-sulphuric acid, sodium nitrite, 2.) sodium azide / 1.) 1,4-dioxan, water, -5 deg C, 30 min
With
hydrogenchloride; phosphorus; N-Bromosuccinimide; sodium azide; sulfuric acid; iodine; sodium nitrite;
In
tetrahydrofuran; tetrachloromethane; diethyl ether; water; acetic acid; toluene;
DOI:10.1039/P19810001132
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / red phosphorus, iodine / acetic acid; H2O / 4 h / Heating
2: 1.) 2N-sulphuric acid, sodium nitrite, 2.) sodium azide / 1.) 1,4-dioxan, water, -5 deg C, 30 min
With
phosphorus; sodium azide; sulfuric acid; iodine; sodium nitrite;
In
water; acetic acid;
DOI:10.1039/P19810001132
