C₁₈H₁₁F₅N₃O⁽¹⁺⁾*Cl^(1-)

Base Information

• Chemical Name: C₁₈H₁₁F₅N₃O⁽¹⁺⁾*Cl^(1-)
• CAS No.: 945656-57-5
• Molecular Formula: C₁₈H₁₁F₅N₃O*Cl
• Molecular Weight: 415.75
• Mol file: 945656-57-5.mol

Synonyms:

Chemical Property of C₁₈H₁₁F₅N₃O⁽¹⁺⁾*Cl^(1-)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₁₈H₁₁F₅N₃O⁽¹⁺⁾*Cl^(1-)

There total 2 articles about C₁₈H₁₁F₅N₃O⁽¹⁺⁾*Cl^(1-) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H12F5N3O*ClH + orthoformic acid triethyl ester (122-51-0) → C18H11F5N3O(1+)*Cl(1-) (945656-57-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; chlorobenzene; at 110 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja302761d

Reference yield:

C12H13O2N + pentafluorophenylhydrazine*hydrochloride (1514-49-4) → C18H11F5N3O(1+)*Cl(1-) (945656-57-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane; methanol / 2.5 h / 60 °C / Inert atmosphere

2: hydrogenchloride / 1,4-dioxane; chlorobenzene / 12 h / 110 °C / Inert atmosphere

With hydrogenchloride; In 1,4-dioxane; methanol; chlorobenzene;

DOI:10.1021/ja302761d

upstream raw materials:

pentafluorophenylhydrazine*hydrochloride

orthoformic acid triethyl ester