ethyl 3-(diethoxymethyl)-5-(1,3-dihydro-2H-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazin-2-yl)pentanoate

Base Information

• Chemical Name: ethyl 3-(diethoxymethyl)-5-(1,3-dihydro-2H-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazin-2-yl)pentanoate
• CAS No.: 39013-42-8
• Molecular Formula: C₃₀H₄₁N₃O₆
• Molecular Weight: 539.672
• Mol file: 39013-42-8.mol

Synonyms:

Chemical Property of ethyl 3-(diethoxymethyl)-5-(1,3-dihydro-2H-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazin-2-yl)pentanoate

Chemical Property:

• Vapor Pressure: 2.74E-18mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-(diethoxymethyl)-5-(1,3-dihydro-2H-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazin-2-yl)pentanoate

There total 3 articles about ethyl 3-(diethoxymethyl)-5-(1,3-dihydro-2H-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazin-2-yl)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-dihydro-1H-pyrrolo[3,4-b]quinoline (34086-64-1) → 3-diethoxymethyl-5-(1,3-dihydro-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-pentanoic acid ethyl ester (39013-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide

2: NaOEt / methanol

With sodium ethanolate; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jo00951a003

Reference yield:

(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-acetic acid ethyl ester (36867-19-3) → 3-diethoxymethyl-5-(1,3-dihydro-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-pentanoic acid ethyl ester (39013-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide

2: NaOEt / methanol

With sodium ethanolate; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jo00951a003

Reference yield:

2-[(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-acetyl]-2,3-dihydro-1H-pyrrolo[3,4-b]quinoline (39013-35-9) + ethyl 4,4-diethoxy-2-butenoate (55531-67-4) → 3-diethoxymethyl-5-(1,3-dihydro-pyrrolo[3,4-b]quinolin-2-yl)-5-oxo-4-(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-pentanoic acid ethyl ester (39013-42-8)

Guidance literature:

With sodium ethanolate; In methanol;

DOI:10.1021/jo00951a003

upstream raw materials:

2-[(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-acetyl]-2,3-dihydro-1H-pyrrolo[3,4-b]quinoline

ethyl 4,4-diethoxy-2-butenoate

2,3-dihydro-1H-pyrrolo[3,4-b]quinoline

(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-acetic acid ethyl ester