(+)-pederol dibenzoate

Base Information

• Chemical Name: (+)-pederol dibenzoate
• CAS No.: 82796-36-9
• Molecular Formula: C₂₇H₃₄O₇
• Molecular Weight: 470.563
• Mol file: 82796-36-9.mol

Synonyms:

Chemical Property of (+)-pederol dibenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-pederol dibenzoate

There total 27 articles about (+)-pederol dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3,4-dimethoxybutan-1-ol (129155-91-5) → C27H34O7 (67213-36-9,67253-69-4,82796-36-9,108267-96-5,129213-87-2,129261-31-0)

Guidance literature:

Multi-step reaction with 11 steps

1: 98 percent / oxalyl chloride, DMSO, N-methylmorpholine / CH₂Cl₂ / 2.5 h / 0 °C

2: 66 percent / TsOH, MgSO₄ / CH₂Cl₂ / 48 h / Ambient temperature

3: 88 percent / liq. ammonia, sodium / diethyl ether / 0.5 h / -78 °C

4: 50 percent / pyridinium chlorochromate, celite / CH₂Cl₂ / 2.5 h / 20 °C

5: 88 percent / tetrahydrofuran / 0.17 h

6: pyridinium chlorochromate, celite / CH₂Cl₂ / 3.5 h

7: 90 percent / 3P>3RhCl / 55 °C

8: 8 percent / TiCl₄ / CH₂Cl₂ / 1 h / -78 °C

9: 58 percent / pyridine

10: NaBH₄ / ethanol / 2 h

11: DMAP, pyridine

With 4-methyl-morpholine; pyridine; dmap; sodium tetrahydroborate; oxalyl dichloride; Celite; ammonia; sodium; titanium tetrachloride; magnesium sulfate; toluene-4-sulfonic acid; dimethyl sulfoxide; pyridinium chlorochromate; Wilkinson's catalyst; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane;

DOI:10.1016/S0040-4020(01)81981-5

Reference yield:

(S)-3,4-dimethoxybutan-1-ol (129155-91-5) → (+)-pederol dibenzoate (82796-36-9)

Guidance literature:

Multi-step reaction with 11 steps

1: 98 percent / oxalyl chloride, DMSO, N-methylmorpholine / CH₂Cl₂ / 2.5 h / 0 °C

2: 66 percent / TsOH, MgSO₄ / CH₂Cl₂ / 48 h / Ambient temperature

3: 88 percent / liq. ammonia, sodium / diethyl ether / 0.5 h / -78 °C

4: 50 percent / pyridinium chlorochromate, celite / CH₂Cl₂ / 2.5 h / 20 °C

5: 88 percent / tetrahydrofuran / 0.17 h

6: pyridinium chlorochromate, celite / CH₂Cl₂ / 3.5 h

7: 90 percent / 3P>3RhCl / 55 °C

8: 8 percent / TiCl₄ / CH₂Cl₂ / 1 h / -78 °C

9: 58 percent / pyridine

10: NaBH₄ / ethanol / 2 h

11: DMAP, pyridine

With 4-methyl-morpholine; pyridine; dmap; sodium tetrahydroborate; oxalyl dichloride; Celite; ammonia; sodium; titanium tetrachloride; magnesium sulfate; toluene-4-sulfonic acid; dimethyl sulfoxide; pyridinium chlorochromate; Wilkinson's catalyst; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane;

DOI:10.1016/S0040-4020(01)81981-5

Reference yield:

2-[(S)-2-((S)-2,3-Dimethoxy-propyl)-[1,3]dioxolan-4-yl]-ethanol (129155-92-6,129155-93-7) → (+)-pederol dibenzoate (82796-36-9)

Guidance literature:

Multi-step reaction with 8 steps

1: 50 percent / pyridinium chlorochromate, celite / CH₂Cl₂ / 2.5 h / 20 °C

2: 88 percent / tetrahydrofuran / 0.17 h

3: pyridinium chlorochromate, celite / CH₂Cl₂ / 3.5 h

4: 90 percent / 3P>3RhCl / 55 °C

5: 8 percent / TiCl₄ / CH₂Cl₂ / 1 h / -78 °C

6: 58 percent / pyridine

7: NaBH₄ / ethanol / 2 h

8: DMAP, pyridine

With pyridine; dmap; sodium tetrahydroborate; Celite; titanium tetrachloride; pyridinium chlorochromate; Wilkinson's catalyst; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1016/S0040-4020(01)81981-5

upstream raw materials:

benzyl chloride

(S)-3,4-dimethoxybutan-1-ol

2-[(S)-2-((S)-2,3-Dimethoxy-propyl)-[1,3]dioxolan-4-yl]-ethanol

(S)-4-benzyloxy-1,2-dimethoxy-butane