C₂₀H₂₀N₂O₂

Base Information

Chemical Name:C₂₀H₂₀N₂O₂
CAS No.:1476042-77-9
Molecular Formula:C₂₀H₂₀N₂O₂
Molecular Weight:320.391
Hs Code.:

C<sub>20</sub>H<sub>20</sub>N<sub>2</sub>O<sub>2</sub>

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₂₀N₂O₂

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Technology Process of C₂₀H₂₀N₂O₂

There total 8 articles about C₂₀H₂₀N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: C₂₀H₂₀N₂O₂

: 1476042-77-9,88460-17-7
C₂₀H₂₀N₂O₂

Guidance literature:: With (+)-N-benzylcinchonineammonium bromide; caesium carbonate; In toluene; at 0 ℃; enantioselective reaction;
DOI:10.1055/s-0033-1339487

Reference yield: 74.0%

: 2-((E)-3-oxo-3-pyrrolidin-1-ylpropenyl)-N-phenylbenzamide

: 1476042-77-9,88460-17-7
C₂₀H₂₀N₂O₂

Guidance literature:: With caesium carbonate; In toluene; at 20 ℃; for 24h;
DOI:10.1002/ejoc.201403573

Reference yield:

: 55666-42-7
tert-butyl 2-bromobenzoate

: 1476042-77-9,88460-17-7
C₂₀H₂₀N₂O₂

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; palladium diacetate; 1,1'-bis-(diphenylphosphino)ferrocene / dimethyl sulfoxide / 12 h / Heating

2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

3: dicyclohexyl-carbodiimide; dmap / dichloromethane / 12 h / 20 °C

4: (+)-N-benzylcinchonineammonium bromide; caesium carbonate / toluene / 0 °C

With dmap; 1,1'-bis-(diphenylphosphino)ferrocene; (+)-N-benzylcinchonineammonium bromide; palladium diacetate; caesium carbonate; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane; dimethyl sulfoxide; toluene; 1: |Heck Reaction;
DOI:10.1055/s-0033-1339487