2-Methyl-1-m-tolyl-cyclopentanol

Base Information

• Chemical Name: 2-Methyl-1-m-tolyl-cyclopentanol
• CAS No.: 97704-19-3
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.285
• Mol file: 97704-19-3.mol

Synonyms:

Chemical Property of 2-Methyl-1-m-tolyl-cyclopentanol

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methyl-1-m-tolyl-cyclopentanol

There total 1 articles about 2-Methyl-1-m-tolyl-cyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methylcyclopentanone (1120-72-5) + meta-bromotoluene (591-17-3) → 2-Methyl-1-m-tolyl-cyclopentanol (97704-19-3)

Guidance literature:

With magnesium; Yield given. Multistep reaction; 1.) Et₂O, reflux, 1.5 h, 2.) Et₂O, reflux, 3 h;

DOI:10.1055/s-1998-2089

Reference yield:

2-Methyl-1-m-tolyl-cyclopentanol (97704-19-3) → 5-Methyl-1-(3-methylphenyl)cyclopentene + 1-Methyl-2-(3-methylphenyl)cyclopentene

Guidance literature:

With toluene-4-sulfonic acid; In toluene; at 110 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1055/s-1998-2089

Reference yield:

2-Methyl-1-m-tolyl-cyclopentanol (97704-19-3) → (+/-)-herbertene (83059-86-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) TsOH, 2.) MCPBA / 1.) toluene, 110 deg C, 3 h, 2.) CH₂Cl₂, 0 deg C, 1 h; 0 deg C to r.t., overnight

2: 38 percent / hexane / 8 h / 0 °C

3: 1.) TiCl₄ / 1.) CH₂Cl₂, 0 deg C, 10 min, 2.) CH₂Cl₂, 0 deg C, 8 h

With titanium tetrachloride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In hexane;

DOI:10.1055/s-1998-2089

upstream raw materials:

2-Methylcyclopentanone

meta-bromotoluene

Downstream raw materials:

1,2-Epoxy-1-methyl-2-(3-methylphenyl)cyclopentane

(+/-)-herbertene

1,2-Dimethyl-2-(3-methylphenyl)cyclopentan-1-ol

1-Methyl-2-(3-methylphenyl)cyclopentane-1,2-diol