syn-Benzo(f)quinoline-7,8-diol-9,10-epoxide

Base Information

Chemical Name:syn-Benzo(f)quinoline-7,8-diol-9,10-epoxide
CAS No.:103620-30-0
Deprecated CAS:103620-30-0
Molecular Formula:C₁₃H₁₁NO₃
Molecular Weight:229.235
Hs Code.:
DSSTox Substance ID:DTXSID00908517,DTXSID601030472
Wikidata:Q82877932

Synonyms:syn-Benzo(f)quinoline-7,8-diol-9,10-epoxide;119239-63-3;CCRIS 2963;12-hydroxy-14-oxa-6-azatetracyclo[8.5.0.02,7.013,15]pentadeca-1(15),2,4,7,9,12-hexaen-11-one;SYN-BENZO[F]QUINOLINE-7,8-DIOL-9,10-EPOXIDE;DTXSID00908517;DTXSID601030472;2-hydroxy[1]benzoxireno[2,3-f]quinolin-3(6H)-one;103620-30-0

Suppliers and Price of syn-Benzo(f)quinoline-7,8-diol-9,10-epoxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of syn-Benzo(f)quinoline-7,8-diol-9,10-epoxide

Chemical Property:

Vapor Pressure:8.14E-11mmHg at 25°C
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:225.042593085
Heavy Atom Count:17
Complexity:669

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CNC2=CC=C3C(=C4C(=C(C3=O)O)O4)C2=C1

Technology Process of syn-Benzo(f)quinoline-7,8-diol-9,10-epoxide

There total 4 articles about syn-Benzo(f)quinoline-7,8-diol-9,10-epoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 103620-29-7
(+/-)-7β,8α-diacetoxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzoquinoline

: 103620-30-0
(+/-)-7β,8α-dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzoquinoline

Guidance literature:: With sodium hydroxide; In methanol; at 0 ℃; for 0.25h;
DOI:10.1021/jo00368a001

Reference yield:

: 103639-19-6
trans-7,8-diacetoxy-7,8-dihydrobenzoquinoline

: 103620-30-0
(+/-)-7β,8α-dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 64 percent / N-bromoacetamide(NBA), concentrated HCl / tetrahydrofuran / 3 h

2: 53 percent / Amberlite / tetrahydrofuran / 8 h / 25 °C

3: 72 percent / 5percent NaOH / methanol / 0.25 h / 0 °C

With hydrogenchloride; sodium hydroxide; Amberlite; N-bromoacetamide; In tetrahydrofuran; methanol;
DOI:10.1021/jo00368a001

Reference yield:

: 103620-28-6
(+/-)-7β,8α-diacetoxy-9α-bromo-10β-hydroxy-7,8,9,10-tetrahydrobenzoquinoline

: 103620-30-0
(+/-)-7β,8α-dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / Amberlite / tetrahydrofuran / 8 h / 25 °C

2: 72 percent / 5percent NaOH / methanol / 0.25 h / 0 °C

With sodium hydroxide; Amberlite; In tetrahydrofuran; methanol;
DOI:10.1021/jo00368a001