3-Pyridineacetic acid, 6-(methoxycarbonyl)-

Base Information

Chemical Name:3-Pyridineacetic acid, 6-(methoxycarbonyl)-
CAS No.:154586-80-8
Molecular Formula:C₉H₉NO₄
Molecular Weight:195.175
Hs Code.:
European Community (EC) Number:831-178-5

Synonyms:154586-80-8;2-[6-(methoxycarbonyl)pyridin-3-yl]acetic acid;3-Pyridineacetic acid, 6-(methoxycarbonyl)-;2-(6-methoxycarbonylpyridin-3-yl)acetic Acid;SCHEMBL9314024;AKOS006311896;2-[6-(methoxycarbonyl)pyridin-3-yl]aceticacid;EN300-344863;Z2738925414

Suppliers and Price of 3-Pyridineacetic acid, 6-(methoxycarbonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Pyridineacetic acid, 6-(methoxycarbonyl)-

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:195.05315777
Heavy Atom Count:14
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=NC=C(C=C1)CC(=O)O

Technology Process of 3-Pyridineacetic acid, 6-(methoxycarbonyl)-

There total 6 articles about 3-Pyridineacetic acid, 6-(methoxycarbonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4434-13-3
2-carboxy-5-methylpyridine

: 154586-80-8
5-Carboxymethyl-pyridine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, hexane, 0 deg C, 2 h, 2.) THF, hexane, RT, 2 h

2: HCl / 72 h / Ambient temperature

3: 57 percent Chromat_. / KOH / methanol / 2 h

With hydrogenchloride; potassium hydroxide; lithium diisopropyl amide; In methanol;
DOI:10.1021/jm9505526

Reference yield:

: 162368-24-3
(6-carboxy-[3]pyridyl)-acetic acid

: 154586-80-8
5-Carboxymethyl-pyridine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / 72 h / Ambient temperature

2: 57 percent Chromat_. / KOH / methanol / 2 h

With hydrogenchloride; potassium hydroxide; In methanol;
DOI:10.1021/jm9505526

Reference yield:

: 43083-20-1
5-chlorocarbonyl-pyridine-2-carboxylic acid methyl ester

: 154586-80-8
5-Carboxymethyl-pyridine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; diethyl ether / 1 h / 0 °C

2: 5 g / silver(I) oxide / 0.33 h / Heating

3: 1.8 g / trifluoroacetic acid (TFA) / 0.33 h / Ambient temperature

With trifluoroacetic acid; silver(l) oxide; In tetrahydrofuran; diethyl ether;
DOI:10.1021/jm00083a001