C₁₉H₂₀FN₃O

Base Information

Chemical Name:C₁₉H₂₀FN₃O
CAS No.:1338494-74-8
Molecular Formula:C₁₉H₂₀FN₃O
Molecular Weight:325.386
Hs Code.:

C<sub>19</sub>H<sub>20</sub>FN<sub>3</sub>O

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₉H₂₀FN₃O

Chemical Property:

Purity/Quality:

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Technology Process of C₁₉H₂₀FN₃O

There total 5 articles about C₁₉H₂₀FN₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1338494-73-7
C₁₅H₁₅FN₂O₂

: 1338494-74-8
C₁₉H₂₀FN₃O

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hydroxide / tetrahydrofuran; water / 2 h / 60 °C

2: N-ethyl-N,N-diisopropylamine; HATU / dimethyl sulfoxide

With N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; water; dimethyl sulfoxide;
DOI:10.1021/ja2066972

Reference yield:

: 2739-98-2
ethyl 2-(pyridinyl-2)acetate

: 1338494-74-8
C₁₉H₂₀FN₃O

Guidance literature:: Multi-step reaction with 5 steps

1.1: carbon tetrabromide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0.5 h / -78 - 20 °C

2.1: triethylamine / tetrahydrofuran / 60 °C

2.2: 2 h / 70 °C

3.1: sodium tetrahydroborate / methanol / 2 h / 0 °C

4.1: lithium hydroxide / tetrahydrofuran; water / 2 h / 60 °C

5.1: N-ethyl-N,N-diisopropylamine; HATU / dimethyl sulfoxide

With sodium tetrahydroborate; carbon tetrabromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; methanol; water; dimethyl sulfoxide;
DOI:10.1021/ja2066972

Reference yield:

: 74376-32-2
ethyl α-bromo-2-pyridylacetate

: 1338494-74-8
C₁₉H₂₀FN₃O

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / tetrahydrofuran / 60 °C

1.2: 2 h / 70 °C

2.1: sodium tetrahydroborate / methanol / 2 h / 0 °C

3.1: lithium hydroxide / tetrahydrofuran; water / 2 h / 60 °C

4.1: N-ethyl-N,N-diisopropylamine; HATU / dimethyl sulfoxide

With sodium tetrahydroborate; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; methanol; water; dimethyl sulfoxide;
DOI:10.1021/ja2066972