*,R^*)>-α-(trifluoromethyl)-α-methoxyphenylacetic acid 3-fluoro-4-hydroxy-4-methylpentyl ester

Base Information

• Chemical Name: *,R^*)>-α-(trifluoromethyl)-α-methoxyphenylacetic acid 3-fluoro-4-hydroxy-4-methylpentyl ester
• CAS No.: 112138-92-8
• Molecular Formula: C₁₆H₂₀F₄O₄
• Molecular Weight: 352.326

Synonyms:

Chemical Property of *,R^*)>-α-(trifluoromethyl)-α-methoxyphenylacetic acid 3-fluoro-4-hydroxy-4-methylpentyl ester

Chemical Property:

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Technology Process of *,R^*)>-α-(trifluoromethyl)-α-methoxyphenylacetic acid 3-fluoro-4-hydroxy-4-methylpentyl ester

There total 1 articles about *,R^*)>-α-(trifluoromethyl)-α-methoxyphenylacetic acid 3-fluoro-4-hydroxy-4-methylpentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride (39637-99-5,20445-33-4) + 3(R)-fluoro-4-methyl-1,4-pentanediol (86677-75-0) → *,R*)>-α-(trifluoromethyl)-α-methoxyphenylacetic acid 3-fluoro-4-hydroxy-4-methylpentyl ester (112138-92-8)

Guidance literature:

With pyridine; at 0 ℃; for 2h;

DOI:10.1021/jo00240a021

upstream raw materials:

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

3(R)-fluoro-4-methyl-1,4-pentanediol

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