C₂₈H₃₂N₆O

Base Information

• Chemical Name: C₂₈H₃₂N₆O
• CAS No.: 481048-78-6
• Molecular Formula: C₂₈H₃₂N₆O
• Molecular Weight: 468.602
• Mol file: 481048-78-6.mol

Synonyms:

Chemical Property of C₂₈H₃₂N₆O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₂N₆O

There total 7 articles about C₂₈H₃₂N₆O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H11ClN2O2 (481049-38-1) → C28H32N6O (481048-78-6)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran / -78 - 0 °C

2: MnO₂ / CH₂Cl₂

3: K₂CO₃ / ethanol / 80 °C

4: rac-BINAP; Cs₂CO₃ / Pd(OAc)2 / 100 °C

With manganese(IV) oxide; potassium carbonate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; In tetrahydrofuran; ethanol; dichloromethane; 4: Buchwald coupling;

DOI:10.1016/j.bmcl.2007.02.079

Reference yield:

C17H13ClN2O2 (481049-39-2) → C28H32N6O (481048-78-6)

Guidance literature:

Multi-step reaction with 3 steps

1: MnO₂ / CH₂Cl₂

2: K₂CO₃ / ethanol / 80 °C

3: rac-BINAP; Cs₂CO₃ / Pd(OAc)2 / 100 °C

With manganese(IV) oxide; potassium carbonate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; In ethanol; dichloromethane; 3: Buchwald coupling;

DOI:10.1016/j.bmcl.2007.02.079

Reference yield:

C17H11ClN2O2 (481049-40-5) → C28H32N6O (481048-78-6)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / ethanol / 80 °C

2: rac-BINAP; Cs₂CO₃ / Pd(OAc)2 / 100 °C

With potassium carbonate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; In ethanol; 2: Buchwald coupling;

DOI:10.1016/j.bmcl.2007.02.079

upstream raw materials:

C₂₃H₂₂ClN₅O

Cyclopentamine

C₁₄H₁₁ClN₂O

C₁₅H₁₁ClN₂O₂

Downstream raw materials:

C₂₇H₃₀N₆O