Technology Process of 3-fluoro-5-(9H-xanthen-9-ylidene)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-ol
There total 2 articles about 3-fluoro-5-(9H-xanthen-9-ylidene)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / -78 - 20 °C
1.2: -78 °C
2.1: palladium diacetate; triphenylphosphine; potassium carbonate / N,N-dimethyl-formamide / 2 h / 100 °C / Microwave irradiation
With
n-butyllithium; palladium diacetate; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1055/s-0032-1317325
DOI:10.1055/s-0032-1317325
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydrogencarbonate; N-benzyl-N,N,N-triethylammonium chloride / N,N-dimethyl-formamide / 0.25 h / Inert atmosphere
1.2: 19 h / 40 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / -78 - 20 °C
2.2: -78 °C
3.1: palladium diacetate; triphenylphosphine; potassium carbonate / N,N-dimethyl-formamide / 2 h / 100 °C / Microwave irradiation
With
n-butyllithium; N-benzyl-N,N,N-triethylammonium chloride; palladium diacetate; sodium hydrogencarbonate; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1055/s-0032-1317325
DOI:10.1055/s-0032-1317325
