Technology Process of epi-nocardicin G-pantetheine trifluoroacetate
There total 10 articles about epi-nocardicin G-pantetheine trifluoroacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; trifluoroacetic acid;
In
acetonitrile;
at 20 ℃;
for 0.25h;
DOI:10.1021/jo4007893
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / 12 h / 20 °C / Molecular sieve
2.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 1 h / 20 °C
2.2: 12 h / 20 °C
3.1: potassium carbonate; (benzotriazol-1-yloxy)tripyrrolodinophosphonium hexafluorophosphate / N,N-dimethyl-formamide / 0.5 h / 20 °C
4.1: trifluoroacetic acid; water / acetonitrile / 0.25 h / 20 °C
With
(benzotriazol-1-yloxy)tripyrrolodinophosphonium hexafluorophosphate; water; potassium carbonate; toluene-4-sulfonic acid; 1,1'-carbonyldiimidazole; trifluoroacetic acid;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo4007893
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 1 h / 20 °C
1.2: 12 h / 20 °C
2.1: potassium carbonate; (benzotriazol-1-yloxy)tripyrrolodinophosphonium hexafluorophosphate / N,N-dimethyl-formamide / 0.5 h / 20 °C
3.1: trifluoroacetic acid; water / acetonitrile / 0.25 h / 20 °C
With
(benzotriazol-1-yloxy)tripyrrolodinophosphonium hexafluorophosphate; water; potassium carbonate; 1,1'-carbonyldiimidazole; trifluoroacetic acid;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo4007893
